s532494

• Gene Symbol: VEGFA
• Gene Name: vascular endothelial growth factor A
• Gene Aliases: MVCD1, VEGF, VPF
• Chromosome Location: Chr.6: 43770209 - 43786487 on Build GRCh38
• UniGene ID: Hs.73793
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: VEGFA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025366.2	NP_001020537.2	7	1694
	NM_001025367.2	NP_001020538.2	7	1625
	NM_001025368.2	NP_001020539.2	6	1571
	NM_001033756.2	NP_001028928.1	6	1571
	NM_001171623.1	NP_001165094.1	7	1694
	NM_001171624.1	NP_001165095.1	7	1643
	NM_001171625.1	NP_001165096.1	7	1625
	NM_001171626.1	NP_001165097.1	6	1571
	NM_001171629.1	NP_001165100.1	6	1571
	NM_001287044.1	NP_001273973.1	6	584
	NM_001317010.1	NP_001303939.1	6	1571
	NM_003376.5	NP_003367.4	7	1643
GenBank mRNA	AB021221.1	-	6	533
	AB209485.1	-	3	7752
	AB451322.1	-	6	533
	AB451451.1	-	6	533
	AF022375.1	-	6	1234
	AF062645.1	-	4	248
	AF430806.1	-	6	533
	AF486837.1	-	6	533
	AJ010438.1	-	7	587
	AY047581.1	-	6	549
	AY500353.1	-	6	532
	AY766116.1	-	6	533
	BQ880667.1	-	1	111
	BX442364.2	-	6	576
	KT581011.1	-	6	533
	M27281.1	-	7	761
	M32977.1	-	6	589
	S85192.1	-	7	724
	X62568.1	-	6	549

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NR_105011, AY033504, AY033508, AF062644, AY702972, and others.
This siRNA also targets the following transcripts in Mouse: AW913188, BC061468, HQ712122, BQ554097, S37052, and others.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ovarian follicle development
patterning of blood vessels
vasculogenesis
response to hypoxia
in utero embryonic development
kidney development
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
cell migration involved in sprouting angiogenesis
positive regulation of neuroblast proliferation
positive regulation of mesenchymal cell proliferation
positive regulation of receptor internalization
platelet degranulation
positive regulation of leukocyte migration
heart morphogenesis
outflow tract morphogenesis
coronary vein morphogenesis
nervous system development
mesoderm development
lactation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of endothelial cell migration
positive regulation of gene expression
monocyte differentiation
macrophage differentiation
lung development
positive regulation of cell migration
regulation of cGMP metabolic process
epithelial cell differentiation
positive regulation of vascular endothelial growth factor receptor signaling pathway
post-embryonic camera-type eye development
positive regulation of protein complex assembly
positive regulation of protein autophosphorylation
activation of protein kinase activity
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
tube formation
endothelial cell chemotaxis
cellular response to vascular endothelial growth factor stimulus
lymph vessel morphogenesis
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
VEGF-activated neuropilin signaling pathway
growth
eye photoreceptor cell development
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
surfactant homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAP kinase activity
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
vascular endothelial growth factor receptor signaling pathway
cell maturation
camera-type eye morphogenesis
cardiac muscle fiber development
branching morphogenesis of an epithelial tube
positive regulation of axon extension involved in axon guidance
artery morphogenesis
positive regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of positive chemotaxis
induction of positive chemotaxis
positive regulation of cellular component movement
positive regulation of cell division
positive regulation of focal adhesion assembly
primitive erythrocyte differentiation
mammary gland alveolus development
cardiac vascular smooth muscle cell development
coronary artery morphogenesis
regulation of transcription from RNA polymerase II promoter in response to hypoxia
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
cellular response to hypoxia
dopaminergic neuron differentiation
commissural neuron axon guidance
positive regulation of protein kinase C signaling
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of branching involved in ureteric bud morphogenesis
regulation of retinal ganglion cell axon guidance
positive regulation of peptidyl-tyrosine autophosphorylation
positive regulation of p38MAPK cascade
positive regulation of histone deacetylase activity
positive regulation of retinal ganglion cell axon guidance
positive regulation of protein kinase D signaling

Function(s)

fibronectin binding
cytokine activity
platelet-derived growth factor receptor binding
vascular endothelial growth factor receptor binding
protein binding
growth factor activity
heparin binding
chemoattractant activity
identical protein binding
protein homodimerization activity
vascular endothelial growth factor receptor 1 binding
vascular endothelial growth factor receptor 2 binding
protein heterodimerization activity
receptor agonist activity
extracellular matrix binding