s533047

• Gene Symbol: TRIM5
• Gene Name: tripartite motif containing 5
• Gene Aliases: RNF88, TRIM5alpha
• Chromosome Location: Chr.11: 5590906 - 5685109 on Build GRCh38
• UniGene ID: Hs.125300
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TRIM5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_033034.2	NP_149023.2	2	322
	NM_033092.2	NP_149083.2	2	322
	NM_033093.2	NP_149084.2	2	174
	XM_005253183.2	XP_005253240.1	2	174
	XM_005253184.2	XP_005253241.1	2	308
	XM_006718358.2	XP_006718421.1	2	308
	XM_011520426.2	XP_011518728.1	2	308
	XM_011520427.1	XP_011518729.1	2	308
	XM_017018460.1	XP_016873949.1	2	308
	XM_017018461.1	XP_016873950.1	2	174
	XM_017018462.1	XP_016873951.1	2	308
	XM_017018463.1	XP_016873952.1	2	174
GenBank mRNA	AB362928.1	-	1	19
	AF220025.1	-	1	81
	AF220026.1	-		81
	AF220027.1	-	1	81
	AF220028.1	-	1	81
	AF220029.1	-	1	81
	AK027593.1	-	2	276
	AY625000.1	-	1	19
	BC020770.1	-	3	445
	BC021258.2	-	2	255	4122548
	DA475412.1	-	2	174
	DQ288685.1	-	1	19
	JF928461.1	-	1	33
	JF928462.1	-	1	33

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

activation of innate immune response
pattern recognition receptor signaling pathway
autophagy
regulation of lipopolysaccharide-mediated signaling pathway
regulation of protein localization
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
innate immune response
negative regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
interferon-gamma-mediated signaling pathway
protein K63-linked ubiquitination
negative regulation of viral release from host cell

Function(s)

ubiquitin-protein transferase activity
protein binding
zinc ion binding
signaling pattern recognition receptor activity
ligase activity
protein kinase binding
protein binding, bridging
identical protein binding
protein homodimerization activity