s534050

• Gene Symbol: MITF
• Gene Name: melanogenesis associated transcription factor
• Gene Aliases: CMM8, MI, WS2, WS2A, bHLHe32
• Chromosome Location: Chr.3: 69739435 - 69968337 on Build GRCh38
• UniGene ID: Hs.166017
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MITF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000248.3	NP_000239.1	2	241
	NM_001184967.1	NP_001171896.1	3	472
	NM_001184968.1	NP_001171897.1	2	241
	NM_006722.2	NP_006713.1	3	467
	NM_198158.2	NP_937801.1	2	241
	NM_198159.2	NP_937802.1	3	602
	NM_198177.2	NP_937820.1	3	458
	XM_005264754.1	XP_005264811.1	3	574
	XM_005264755.3	XP_005264812.1	3	600
	XM_006713164.2	XP_006713227.1	4	594
	XM_011533722.2	XP_011532024.1	3	579
	XM_011533723.2	XP_011532025.1	3	599
	XM_017006444.1	XP_016861933.1	3	8789
	XM_017006445.1	XP_016861934.1	3	579
	XM_017006446.1	XP_016861935.1	3	441
	XM_017006447.1	XP_016861936.1	4	710
	XM_017006448.1	XP_016861937.1	4	594
GenBank mRNA	AB006909.1	-	3	555
	AK291318.1	-	3	574
	AK296129.1	-	3	472
	AK297858.1	-	3	404
	AL110195.1	-	3	558
	BC026961.2	-	2	171	3924101
	BC065243.1	-	2	198	6066096
	BQ219650.1	-	2	241
	DC388606.1	-	3	459
	Z29678.1	-	2	238

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	DC422081.1	-	3	458		Chr. 3 - 69866224 - 69937980 [+] on Build GRCh38
GenBankmRNA	BP277367.1	-	3	460		Chr. 3 - 69866225 - 69938013 [+] on Build GRCh38
GenBankmRNA	DC361712.1	-	3	458		Chr. 3 - 69866224 - 69938033 [+] on Build GRCh38
GenBankmRNA	HY180835.1	-	3	457		Chr. 3 - 69838512 - 69937953 [+] on Build GRCh38
GenBankmRNA	DC354465.1	-	3	458		Chr. 3 - 69866224 - 69938035 [+] on Build GRCh38
GenBankmRNA	CN481686.1	-	3	425		Chr. 3 - 69866257 - 69939153 [+] on Build GRCh38
GenBankmRNA	HY163756.1	-	3	429		Chr. 3 - 69866253 - 69938011 [+] on Build GRCh38
GenBankmRNA	DC362352.1	-	3	458		Chr. 3 - 69866224 - 69938009 [+] on Build GRCh38
GenBankmRNA	DC392461.1	-	3	458		Chr. 3 - 69866224 - 69938028 [+] on Build GRCh38
GenBankmRNA	HY173803.1	-	3	454		Chr. 3 - 69838514 - 69937934 [+] on Build GRCh38
GenBankmRNA	DC362311.1	-	3	440		Chr. 3 - 69866242 - 69938042 [+] on Build GRCh38
GenBankmRNA	DC362467.1	-	3	446		Chr. 3 - 69866236 - 69938034 [+] on Build GRCh38
GenBankmRNA	BP276751.1	-	3	457		Chr. 3 - 69866224 - 69938030 [+] on Build GRCh38

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AK052895, AK155350, BC108976, Z23066, AB221657, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
multicellular organism development
positive regulation of gene expression
protein sumoylation
melanocyte differentiation
regulation of apoptotic process
regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mast cell migration
positive regulation of DNA-templated transcription, initiation
regulation of RNA biosynthetic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
protein dimerization activity