s534739

• Gene Symbol: PAK3
• Gene Name: p21 (RAC1) activated kinase 3
• Gene Aliases: ARA, MRX30, MRX47, OPHN3, PAK-3, PAK3beta, bPAK, beta-PAK
• Chromosome Location: Chr.X: 110944241 - 111227361 on Build GRCh38
• UniGene ID: Hs.593599
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PAK3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001128166.2	NP_001121638.1	4	713
	NM_001128167.2	NP_001121639.1	3	640
	NM_001128168.2	NP_001121640.1	6	854
	NM_001128172.2	NP_001121644.1	2	252
	NM_001128173.2	NP_001121645.1	6	854
	NM_001324325.1	NP_001311254.1	4	791
	NM_001324326.1	NP_001311255.1	4	636
	NM_001324327.1	NP_001311256.1	5	703
	NM_001324328.1	NP_001311257.1	4	636
	NM_001324329.1	NP_001311258.1	6	851
	NM_001324330.1	NP_001311259.1	4	788
	NM_001324331.1	NP_001311260.1	5	703
	NM_001324332.1	NP_001311261.1	6	854
	NM_001324333.1	NP_001311262.1	5	784
	NM_001324334.1	NP_001311263.1	5	784
	NM_002578.4	NP_002569.1	6	851
	NR_136747.1		5	703
	NR_136748.1		3	400
	XM_005262132.2	XP_005262189.1	6	846
	XM_005262133.3	XP_005262190.1	6	846
	XM_006724654.2	XP_006724717.1	5	693
	XM_006724655.2	XP_006724718.1	4	636
	XM_011530962.1	XP_011529264.1	6	844
	XM_011530967.2	XP_011529269.1	5	784
	XM_011530968.2	XP_011529270.1	6	860
	XM_011530969.1	XP_011529271.1	4	705
	XM_011530971.2	XP_011529273.1	6	846
	XM_017029557.1	XP_016885046.1	4	705
	XM_017029558.1	XP_016885047.1	5	693
	XM_017029559.1	XP_016885048.1	4	705
	XM_017029560.1	XP_016885049.1	4	636
	XM_017029561.1	XP_016885050.1	6	853
	XM_017029562.1	XP_016885051.1	6	846
	XM_017029563.1	XP_016885052.1	6	846
GenBank mRNA	AB102659.1	-	2	225
	AF068864.1	-	2	225
	AK128022.1	-	5	939
	AK290504.1	-	3	640
	AK315284.1	-	4	557
	AM943850.1	-	2	225
	AM943851.1	-	2	225
	AM943852.1	-	2	225
	BC117353.1	-	3	319
	BC117355.1	-	3	319
	BC143544.1	-	3	319

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: U33314.
This siRNA also targets the following transcripts in Mouse: AJ496262, BC053403, U39738, AJ496263, AF082297, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
mitotic cell cycle
stimulatory C-type lectin receptor signaling pathway
axonogenesis
dendrite development
regulation of actin filament polymerization
T cell costimulation
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
synapse organization
T cell receptor signaling pathway
dendritic spine morphogenesis
positive regulation of dendritic spine morphogenesis
cellular response to organic cyclic compound
positive regulation of DNA biosynthetic process

Function(s)

protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
MAP kinase kinase activity
protein binding
ATP binding
Rho GTPase binding
SH3 domain binding
metal ion binding