s536601

• Gene Symbol: HNF1B
• Gene Name: HNF1 homeobox B
• Gene Aliases: FJHN, HNF-1-beta, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1
• Chromosome Location: Chr.17: 37686431 - 37745078 on Build GRCh38
• UniGene ID: Hs.191144
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HNF1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001165923.3	NP_001159395.1	2, 3	743
	NM_001304286.1	NP_001291215.1	2, 3	743
	XM_011525164.1	XP_011523466.1	2, 3	724
GenBank mRNA	AK296633.1	-	2, 3	724
	HM116553.1	-	2, 3	683
	HM116554.1	-	2, 3	683
	HM116556.1	-	2, 3	683

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: EF121974.
This siRNA also targets the following transcripts in Mouse: NM_001291268, AB008175, AK019258, AB008177.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate specification
kidney development
inner cell mass cell differentiation
transcription, DNA-templated
Notch signaling pathway
response to glucose
anterior/posterior pattern specification
response to organic cyclic compound
insulin secretion
regulation of Wnt signaling pathway
hindbrain development
circadian regulation of gene expression
regulation of pronephros size
pronephric nephron tubule development
response to drug
regulation of endodermal cell fate specification
positive regulation of transcription, DNA-templated
embryonic digestive tract morphogenesis
branching morphogenesis of an epithelial tube
pronephros development
epithelial cell proliferation
positive regulation of transcription initiation from RNA polymerase II promoter
ureteric bud elongation
hepatoblast differentiation
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
protein-DNA complex assembly
hepatocyte differentiation
regulation of branch elongation involved in ureteric bud branching
mesonephric duct formation
negative regulation of mesenchymal cell apoptotic process involved in metanephros development

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
core promoter proximal region DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein complex binding
protein homodimerization activity
protein heterodimerization activity