s55345

• Gene Symbol: DHFR
• Gene Name: dihydrofolate reductase
• Gene Aliases: DHFRP1, DYR
• Chromosome Location: Chr.5: 80626226 - 80654981 on Build GRCh38
• UniGene ID: Hs.592364
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DHFR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000791.3	NP_000782.1	2, 3	628
	NM_001290357.1	NP_001277286.1	2, 3	628
GenBank mRNA	AK297302.1	-	2, 3	199
	AK312642.1	-	1	172
	BC000192.1	-	2, 3	191	3352539
	BC003584.1	-	3, 4	590	3354190
	BC070280.1	-	2, 3	173	6714220
	BC071996.1	-	3, 4	590	4645596
	CB988944.1	-	2, 3	657
	EU145592.1	-	1	136
	J00140.1	-	2, 3	178
	V00507.1	-	1	136

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_130400, BC158583, AF318150.

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
glycine biosynthetic process
tetrahydrobiopterin biosynthetic process
one-carbon metabolic process
nucleotide biosynthetic process
axon regeneration
response to methotrexate
dihydrofolate metabolic process
tetrahydrofolate metabolic process
tetrahydrofolate biosynthetic process
folic acid metabolic process
positive regulation of nitric-oxide synthase activity
oxidation-reduction process
regulation of removal of superoxide radicals

Function(s)

mRNA binding
dihydrofolate reductase activity
folic acid binding
drug binding
folate reductase activity
methotrexate binding
NADPH binding