s57486

• Gene Symbol: DVL1
• Gene Name: dishevelled segment polarity protein 1
• Gene Aliases: DRS2, DVL, DVL1L1, DVL1P1
• Chromosome Location: Chr.1: 1335278 - 1349142 on Build GRCh38
• UniGene ID: Hs.731450
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DVL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004421.2	NP_004412.2	7	807
	XM_005244731.3	XP_005244788.1	7	837
	XM_005244732.3	XP_005244789.1	7	837
	XM_005244733.3	XP_005244790.1	7	836
GenBank mRNA	AB209210.1	-	3	613
	AF006011.1	-	7	763
	AK293286.1	-	7	613
	BC017225.2	-	5	532
	BP305846.1	-	6	566

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031820, AF143545, AF143546.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of neurotransmitter levels
positive regulation of protein phosphorylation
transcription from RNA polymerase II promoter
negative regulation of protein kinase activity
neurotransmitter secretion
axon guidance
synapse assembly
heart development
neuromuscular junction development
positive regulation of neuron projection development
neural tube development
convergent extension involved in neural plate elongation
positive regulation of Wnt signaling pathway
cytoplasmic microtubule organization
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
social behavior
protein localization to microtubule
intracellular signal transduction
receptor clustering
positive regulation of transcription, DNA-templated
collateral sprouting
axon extension
dendrite morphogenesis
synapse organization
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
prepulse inhibition
skeletal muscle acetylcholine-gated channel clustering
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
positive regulation of canonical Wnt signaling pathway
positive regulation of protein localization to synapse
regulation of cellular protein localization
beta-catenin destruction complex disassembly

Function(s)

molecular_function
frizzled binding
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
identical protein binding
Rac GTPase binding