s5818

• Gene Symbol: GLI2
• Gene Name: GLI family zinc finger 2
• Gene Aliases: CJS, HPE9, PHS2, THP1, THP2
• Chromosome Location: Chr.2: 120797291 - 120992653 on Build GRCh38
• UniGene ID: Hs.111867
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GLI2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005270.4	NP_005261.2	4	561
	XM_006712422.2	XP_006712485.1	4	561
	XM_011510969.2	XP_011509271.2	4	1193
	XM_011510970.2	XP_011509272.1	4	2204
	XM_011510971.2	XP_011509273.1	4	1454
	XM_011510972.2	XP_011509274.2	4	591
	XM_011510973.2	XP_011509275.1	3	342
	XM_011510974.2	XP_011509276.1	3	401
	XM_017003818.1	XP_016859307.1	4	1193
GenBank mRNA	AY493737.1	-	4	507
	BC111410.1	-	4	556
	DQ004396.1	-	3	401
	DQ086814.1	-	4	531

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107169, XM_008769455.
This siRNA also targets the following transcripts in Mouse: NM_001081125, AM262742, AM262744, X99104, AM261669, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
in utero embryonic development
kidney development
chondrocyte differentiation
osteoblast development
transcription from RNA polymerase II promoter
smoothened signaling pathway
pattern specification process
axon guidance
ventral midline development
hindgut morphogenesis
heart development
cell proliferation
regulation of smoothened signaling pathway
response to mechanical stimulus
anterior/posterior pattern specification
proximal/distal pattern formation
floor plate formation
spinal cord dorsal/ventral patterning
ventral spinal cord development
cerebellar cortex morphogenesis
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
spinal cord ventral commissure morphogenesis
pituitary gland development
lung development
mammary gland development
hindbrain development
negative regulation of chondrocyte differentiation
positive regulation of T cell differentiation in thymus
tube development
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
negative regulation of apoptotic process
positive regulation of neuron differentiation
positive regulation of DNA replication
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract development
developmental growth
neuron development
branching morphogenesis of an epithelial tube
notochord regression
prostatic bud formation
mammary gland duct morphogenesis
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
cellular response to organic cyclic compound
cochlea morphogenesis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding