s61201

• Gene Symbol: SCN5A
• Gene Name: sodium voltage-gated channel alpha subunit 5
• Gene Aliases: CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
• Chromosome Location: Chr.3: 38548061 - 38649673 on Build GRCh38
• UniGene ID: Hs.517898
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SCN5A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000335.4	NP_000326.2	28	5694
	NM_001099404.1	NP_001092874.1	28	5697
	NM_001099405.1	NP_001092875.1	27	5643
	NM_001160160.1	NP_001153632.1	28	5599
	NM_001160161.1	NP_001153633.1	27	5536
	NM_198056.2	NP_932173.1	28	5697
	XM_011533991.2	XP_011532293.1	28	5689
	XM_017007017.1	XP_016862506.1	27	5530
GenBank mRNA	AB158469.2	-	27	5545
	AB158470.2	-	26	5383
	AB208866.1	-	18	4184
	AF482988.1	-	27	5509
	AY038064.1	-	27	5558
	AY148488.1	-	27	5500
	BC140813.1	-	27	5429	9021681
	BC144621.1	-	27	5429	9053152
	EF629346.1	-	27	5545
	EF629347.1	-	26	5491
	KC858891.1	-	26	5446
	M77235.1	-	28	5653

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013125, NM_001160162, XM_006244076, XM_008766670, XM_008766671, and others.

Panther Classification:

Molecular Function -

voltage-gated ion channel

Gene Ontology Categories:

Process(es)

regulation of heart rate
cardiac ventricle development
brainstem development
sodium ion transport
positive regulation of sodium ion transport
response to denervation involved in regulation of muscle adaptation
neuronal action potential
telencephalon development
cerebellum development
sodium ion transmembrane transport
odontogenesis of dentin-containing tooth
positive regulation of action potential
positive regulation of epithelial cell proliferation
membrane depolarization
cardiac muscle contraction
regulation of postsynaptic membrane potential
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of atrial cardiac muscle cell membrane depolarization
regulation of atrial cardiac muscle cell membrane repolarization
regulation of ventricular cardiac muscle cell membrane depolarization
cardiac conduction
cellular response to calcium ion
cardiac muscle cell action potential involved in contraction
regulation of cardiac muscle cell contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
SA node cell action potential
AV node cell action potential
bundle of His cell action potential
membrane depolarization during AV node cell action potential
membrane depolarization during SA node cell action potential
membrane depolarization during Purkinje myocyte cell action potential
membrane depolarization during bundle of His cell action potential
AV node cell to bundle of His cell communication
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transport

Function(s)

voltage-gated sodium channel activity
protein binding
calmodulin binding
fibroblast growth factor binding
enzyme binding
protein kinase binding
protein domain specific binding
ankyrin binding
ubiquitin protein ligase binding
ion channel binding
nitric-oxide synthase binding
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
voltage-gated sodium channel activity involved in AV node cell action potential
voltage-gated sodium channel activity involved in bundle of His cell action potential
voltage-gated sodium channel activity involved in Purkinje myocyte action potential
voltage-gated sodium channel activity involved in SA node cell action potential
scaffold protein binding