s6286

• Gene Symbol: MSH6
• Gene Name: mutS homolog 6
• Gene Aliases: GTBP, GTMBP, HNPCC5, HSAP, p160
• Chromosome Location: Chr.2: 47783082 - 47806953 on Build GRCh38
• UniGene ID: Hs.445052
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MSH6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000179.2	NP_000170.1	4	3164
	NM_001281492.1	NP_001268421.1	2	2774
	NM_001281493.1	NP_001268422.1	3	2994
	NM_001281494.1	NP_001268423.1	4	2899
	XM_011532798.1	XP_011531100.1	4	2871
	XM_011532799.1	XP_011531101.1	4	2946
GenBank mRNA	AK130683.1	-	1	1703
	AK293921.1	-	2	2673
	AK304735.1	-	4	2899
	BC004246.1	-	4	3064	3629489
	BC071594.1	-	3	2997
	D89646.1	-	4	3095
	U28946.1	-	4	3099
	U54777.2	-	4	3082

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_006239735.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
DNA repair
mismatch repair
reciprocal meiotic recombination
determination of adult lifespan
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
viral process
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
maintenance of DNA repeat elements
isotype switching
positive regulation of isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
intrinsic apoptotic signaling pathway

Function(s)

magnesium ion binding
four-way junction DNA binding
chromatin binding
double-stranded DNA binding
protein binding
ATP binding
ATPase activity
mismatched DNA binding
guanine/thymine mispair binding
single guanine insertion binding
single thymine insertion binding
oxidized purine DNA binding
MutLalpha complex binding
methylated histone binding
protein homodimerization activity
ADP binding