s63018

• Gene Symbol: Bmp2
• Gene Name: bone morphogenetic protein 2
• Gene Aliases: AI467020, Bmp2a
• Chromosome Location: Chr.2: 133552159 - 133562896 on Build GRCm38
• UniGene ID: Mm.103205
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bmp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007553.3	NP_031579.2	3	2314
GenBank mRNA	AK132433.1	-	3	2279
	AK133923.1	-	3	2314
	AK161862.1	-	3	2118
	BC100344.1	-	3	1274	30846365

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017178, XM_008762246, L20678, Z25868.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
ossification
osteoblast differentiation
branching involved in ureteric bud morphogenesis
response to hypoxia
in utero embryonic development
epithelial to mesenchymal transition
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
chondrocyte differentiation
BMP signaling pathway involved in heart induction
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
negative regulation of Wnt signaling pathway involved in heart development
proteoglycan metabolic process
regulation of transcription, DNA-templated
protein phosphorylation
transforming growth factor beta receptor signaling pathway
Notch signaling pathway
multicellular organism development
heart development
negative regulation of cell proliferation
embryo development
organ morphogenesis
positive regulation of gene expression
negative regulation of gene expression
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of steroid biosynthetic process
positive regulation of phosphatase activity
telencephalon development
telencephalon regionalization
cell differentiation
positive regulation of Wnt signaling pathway
bone mineralization
positive regulation of cell migration
positive regulation of bone mineralization
BMP signaling pathway
protein destabilization
negative regulation of aldosterone biosynthetic process
positive regulation of osteoblast proliferation
cardiocyte differentiation
embryonic heart tube anterior/posterior pattern specification
bone mineralization involved in bone maturation
growth
odontogenesis of dentin-containing tooth
positive regulation of odontogenesis
regulation of odontogenesis of dentin-containing tooth
regulation of apoptotic process
positive regulation of apoptotic process
regulation of MAPK cascade
positive regulation of MAPK cascade
negative regulation of insulin-like growth factor receptor signaling pathway
cell fate commitment
positive regulation of cell differentiation
positive regulation of fat cell differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
positive regulation of astrocyte differentiation
mesenchymal cell differentiation
inner ear development
positive regulation of neurogenesis
negative regulation of calcium-independent cell-cell adhesion
cartilage development
cardiac muscle cell differentiation
cardiac muscle tissue morphogenesis
oxidation-reduction process
pericardium development
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
cardiac epithelial to mesenchymal transition
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
mesenchyme development
positive regulation of Wnt signaling pathway by BMP signaling pathway
positive regulation of cartilage development
positive regulation of ERK1 and ERK2 cascade
cellular response to growth factor stimulus
cellular response to organic cyclic compound
cellular response to BMP stimulus
mesenchymal cell proliferation involved in ureteric bud development
positive regulation of p38MAPK cascade
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
negative regulation of cortisol biosynthetic process
negative regulation of cardiac muscle cell differentiation

Function(s)

retinol dehydrogenase activity
receptor binding
cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
phosphatase activator activity
protein domain specific binding
protein homodimerization activity
SMAD binding
protein heterodimerization activity
BMP receptor binding