s63126

• Gene Symbol: Btrc
• Gene Name: beta-transducin repeat containing protein
• Gene Aliases: Beta-Trcp1, E3RS-IkappaB, E3RSIkappaB, FWD1, Fbw1a, HOS, Slimb, b-TrCP, beta-TrCP
• Chromosome Location: Chr.19: 45363714 - 45533343 on Build GRCm38
• UniGene ID: Mm.119717
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Btrc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001037758.2	NP_001032847.2	3	310
	NM_001286465.1	NP_001273394.1	3	310
	NM_001286466.1	NP_001273395.1	3	310
	NM_009771.3	NP_033901.1	2	202
GenBank mRNA	AF081887.1	-	2	187
	AF099932.1	-	2	97
	AF110396.1	-	2	97
	AF112979.1	-	2	97
	AK032221.1	-	3	273
	AK052317.1	-	4	334
	AK083257.1	-	3	285
	AK145091.1	-	3	246
	AK145624.1	-	3	293
	AK156660.1	-	2	230
	AK165386.1	-	5	673
	AK180045.1	-	3	189
	AK189588.1	-	2	81
	AK220183.1	-	3	308
	BC003989.1	-	2	103	3491843
	BY070850.1	-	3	307

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_033637, NM_003939, AF129530, BC027994, GU727631, and others.
This siRNA also targets the following transcripts in Rat: NM_001007148, XM_006231530, XM_006231529, XM_006231536, XM_006231541, and others.

Gene Ontology Categories:

Process(es)

protein polyubiquitination
protein dephosphorylation
ubiquitin-dependent protein catabolic process
Wnt signaling pathway
protein ubiquitination
protein catabolic process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
mammary gland epithelial cell proliferation
regulation of circadian rhythm
positive regulation of circadian rhythm
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of cell cycle
branching involved in mammary gland duct morphogenesis
regulation of proteasomal protein catabolic process
cellular response to organic cyclic compound

Function(s)

ubiquitin-protein transferase activity
protein binding
beta-catenin binding
protein phosphorylated amino acid binding
protein dimerization activity
ubiquitin protein ligase activity