s63425

• Gene Symbol: Cav1
• Gene Name: caveolin 1, caveolae protein
• Gene Aliases: Cav, Cav-1
• Chromosome Location: Chr.6: 17306335 - 17341328 on Build GRCm38
• UniGene ID: Mm.28278
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cav1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243064.1	NP_001229993.1	1, 2	399
	NM_007616.4	NP_031642.1	2, 3	303
GenBank mRNA	AB029929.1	-	2, 3	268
	AB029930.1	-	1, 2	316
	AK003489.1	-	2, 3	251
	AK028738.1	-	2, 3	237
	AK035592.1	-	2, 3	241
	AK090074.1	-	1, 2	319
	AY439333.1	-	2, 3	222
	BC038280.1	-	2, 3	211	4484857
	BC052859.1	-	2, 3	214	30062454
	BY235137.1	-	2, 3	278
	CK622116.1	-	1, 2	399
	U07645.1	-	2, 3	188

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133651, NM_031556, XM_006236131, XM_006236130, FM039194, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
inactivation of MAPK activity
angiogenesis
vasculogenesis
response to hypoxia
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
negative regulation of cytokine-mediated signaling pathway
regulation of the force of heart contraction
response to ischemia
regulation of the force of heart contraction by chemical signal
triglyceride metabolic process
calcium ion transport
cellular calcium ion homeostasis
endocytosis
regulation of smooth muscle contraction
skeletal muscle tissue development
lactation
protein localization
negative regulation of cell proliferation
response to mechanical stimulus
positive regulation of signal transduction
negative regulation of signal transduction
positive regulation of calcium ion transport into cytosol
posttranscriptional regulation of gene expression
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
positive regulation of peptidase activity
receptor-mediated endocytosis of virus by host cell
regulation of fatty acid metabolic process
lipid storage
regulation of blood coagulation
negative regulation of BMP signaling pathway
negative regulation of epithelial cell differentiation
mammary gland development
positive regulation of microtubule polymerization
T cell costimulation
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
negative regulation of protein binding
positive regulation of protein binding
maintenance of protein location in cell
response to progesterone
negative regulation of peptidyl-serine phosphorylation
positive regulation of peptidyl-serine phosphorylation
cholesterol efflux
nitric oxide homeostasis
positive regulation of toll-like receptor 3 signaling pathway
wound healing
vasoconstriction
negative regulation of tyrosine phosphorylation of Stat5 protein
cholesterol homeostasis
positive regulation of catalytic activity
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
response to estrogen
negative regulation of nitric oxide biosynthetic process
negative regulation of neuron differentiation
positive regulation of endocytosis
positive regulation of vasoconstriction
negative regulation of JAK-STAT cascade
microtubule polymerization
negative regulation of pinocytosis
negative regulation of smooth muscle cell proliferation
negative regulation of nitric-oxide synthase activity
protein oligomerization
protein homooligomerization
regulation of cytosolic calcium ion concentration
response to calcium ion
membrane depolarization
regulation of peptidase activity
calcium ion homeostasis
mammary gland involution
positive regulation of cell adhesion molecule production
negative regulation of protein tyrosine kinase activity
negative regulation of ERK1 and ERK2 cascade
caveola assembly
cellular response to mechanical stimulus
cellular response to exogenous dsRNA
cellular response to peptide hormone stimulus
cellular response to hyperoxia
cellular response to transforming growth factor beta stimulus
caveolin-mediated endocytosis
regulation of heart rate by cardiac conduction
angiotensin-activated signaling pathway involved in heart process
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
cellular senescence
apoptotic signaling pathway
regulation of membrane repolarization during action potential
regulation of ventricular cardiac muscle cell action potential
negative regulation of peptidyl-tyrosine autophosphorylation
negative regulation of potassium ion transmembrane transport
regulation of cell communication by electrical coupling involved in cardiac conduction
regulation of inward rectifier potassium channel activity
positive regulation of gap junction assembly
receptor internalization involved in canonical Wnt signaling pathway
negative regulation of anoikis
positive regulation of extrinsic apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway
negative regulation of cation channel activity

Function(s)

SNARE binding
RNA polymerase I transcription factor binding
receptor binding
structural molecule activity
protein binding
peptidase activator activity
enzyme binding
kinase binding
protein kinase binding
syntaxin binding
protein binding, bridging
protein complex scaffold
identical protein binding
ion channel binding
protein heterodimerization activity
nitric-oxide synthase binding
ATPase binding
inward rectifier potassium channel inhibitor activity
MDM2/MDM4 family protein binding