s64085

• Gene Symbol: Cxcr2
• Gene Name: chemokine (C-X-C motif) receptor 2
• Gene Aliases: CD128, CDw128, Cmkar2, Gpcr16, IL-8Rh, IL-8rb, IL8RA, Il8rb, mIL-8RH
• Chromosome Location: Chr.1: 74153994 - 74161246 on Build GRCm38
• UniGene ID: Mm.234466
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cxcr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009909.3	NP_034039.1	2	983
GenBank mRNA	AK158234.1	-	3	989
	BC051677.1	-	3	956	30023687
	D17630.1	-	2	979

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017183, XM_008767215, XM_008767214, XM_008767213, X77797.

• Set Membership: G-protein coupled receptor

Gene Ontology Categories:

Process(es)

acute inflammatory response to antigenic stimulus
positive regulation of leukocyte chemotaxis
chemotaxis
cellular defense response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
positive regulation of cell proliferation
positive regulation of cardiac muscle cell apoptotic process
neutrophil chemotaxis
receptor internalization
negative regulation of neutrophil apoptotic process
interleukin-8-mediated signaling pathway
neutrophil activation
negative regulation of apoptotic process
positive regulation of vascular permeability
positive regulation of angiogenesis
chemokine-mediated signaling pathway
metanephric tubule morphogenesis
positive regulation of neutrophil chemotaxis

Function(s)

signal transducer activity
interleukin-8 receptor activity
G-protein coupled receptor activity
chemokine receptor activity
protein binding
C-X-C chemokine receptor activity
interleukin-8 binding