s653 Validated

• Gene Symbol: HTRA2
• Gene Name: HtrA serine peptidase 2
• Gene Aliases: OMI, PARK13, PRSS25
• Chromosome Location: Chr.2: 74529405 - 74533556 on Build GRCh38
• UniGene ID: Hs.469045
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HTRA2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321727.1	NP_001308656.1	1	1082
	NM_001321728.1	NP_001308657.1	1	1082
	NM_013247.4	NP_037379.1	1	1082
	NM_145074.2	NP_659540.1	1	1082
	NR_135769.1		1	1082
	NR_135770.1		2	550
	NR_135771.1		2	534
	NR_135772.1		2	554
GenBank mRNA	AF020760.2	-	1	497
	AF141305.1	-	1	1082
	AF141306.1	-	1	441
	AF141307.1	-	1	318
	AF184911.1	-	1	497
	AK225932.1	-	1	515
	AK291977.1	-	1	501
	BC000096.2	-	1	508	3508944

More Information

Matching Taqman Gene Expression Assay:

Hs00376860_g1

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

proteolysis
ceramide metabolic process
mitochondrion organization
adult walking behavior
intrinsic apoptotic signaling pathway in response to DNA damage
response to herbicide
positive regulation of cell death
protein autoprocessing
pentacyclic triterpenoid metabolic process
forebrain development
cellular response to oxidative stress
cellular response to heat
cellular response to interferon-beta
regulation of multicellular organism growth
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
cellular protein catabolic process
negative regulation of cell cycle
neuron development
cellular response to retinoic acid
cellular response to growth factor stimulus
execution phase of apoptosis
negative regulation of neuron death
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

serine-type endopeptidase activity
protein binding
peptidase activity
serine-type peptidase activity
unfolded protein binding