s65635

• Gene Symbol: Erbb2
• Gene Name: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
• Gene Aliases: Erbb-2, HER-2, HER2, Neu, c-erbB2, c-neu, mKIAA3023
• Chromosome Location: Chr.11: 98412484 - 98437716 on Build GRCm38
• UniGene ID: Mm.290822
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Erbb2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001003817.1	NP_001003817.1	22	2858
GenBank mRNA	AK031099.1	-	22	2726
	AK031542.1	-	14	1556
	AK083669.1	-	21	2808
	AK129487.1	-	22	2828
	AK142296.1	-	22	2852
	BC027080.1	-	4	470
	BC046553.1	-	8	1213
	BC046811.1	-	21	2930	5702040
	BC053078.1	-	21	2930	5702040
	U71126.1	-	3	324

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017003, XM_006247245, BC061863, X03362, AY116182.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
peripheral nervous system development
heart development
neuromuscular junction development
motor neuron axon guidance
positive regulation of cell proliferation
glial cell differentiation
phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
phosphorylation
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
regulation of microtubule-based process
negative regulation of immature T cell proliferation in thymus
wound healing
myelination
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of GTPase activity
estrous cycle
positive regulation of translation
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase III promoter
positive regulation of Ras protein signal transduction
protein autophosphorylation
sympathetic nervous system development
response to axon injury
oligodendrocyte differentiation
positive regulation of epithelial cell proliferation
regulation of ERK1 and ERK2 cascade

Function(s)

nucleotide binding
RNA polymerase I core binding
glycoprotein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
transmembrane signaling receptor activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
protein heterodimerization activity
Hsp90 protein binding