s65794

• Gene Symbol: F2rl1
• Gene Name: coagulation factor II (thrombin) receptor-like 1
• Gene Aliases: Gpcr11, PAR-2, Par2
• Chromosome Location: Chr.13: 95511718 - 95525240 on Build GRCm38
• UniGene ID: Mm.1614
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: F2rl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007974.4	NP_032000.3	2	1155
GenBank mRNA	AK144986.1	-	2	1139
	AK158462.1	-	2	1143
	AK160916.1	-	2	1143
	AX785009.1	-	2	1114
	BC025432.1	-	2	1140	5006769
	Z48043.1	-	2	1114

More Information

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

T cell activation involved in immune response
immune system process
positive regulation of leukocyte chemotaxis
positive regulation of cytokine secretion involved in immune response
positive regulation of glomerular filtration
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood coagulation
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of phosphatidylinositol 3-kinase signaling
regulation of blood coagulation
positive regulation of cell migration
positive regulation of actin filament depolymerization
positive regulation of pseudopodium assembly
positive regulation of superoxide anion generation
positive regulation of toll-like receptor 2 signaling pathway
negative regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
positive regulation of Rho protein signal transduction
chemokine (C-C motif) ligand 2 secretion
neutrophil activation
regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of eosinophil degranulation
innate immune response
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
regulation of JNK cascade
negative regulation of JNK cascade
positive regulation of JNK cascade
interleukin-1 beta secretion
leukocyte migration
positive regulation of chemotaxis
positive regulation of positive chemotaxis
defense response to virus
positive regulation of phagocytosis, engulfment
establishment of endothelial barrier
positive regulation of ERK1 and ERK2 cascade
thrombin receptor signaling pathway
leukocyte proliferation
positive regulation of neutrophil mediated killing of gram-negative bacterium
interleukin-10 secretion
interferon-gamma secretion
chemokine secretion
negative regulation of chemokine secretion
mature conventional dendritic cell differentiation
positive regulation of renin secretion into blood stream
positive regulation of interleukin-8 secretion
positive regulation of interleukin-6 secretion

Function(s)

G-protein alpha-subunit binding
signal transducer activity
G-protein coupled receptor activity
thrombin receptor activity
G-protein beta-subunit binding
heterotrimeric G-protein binding