s66151

• Gene Symbol: Flt1
• Gene Name: FMS-like tyrosine kinase 1
• Gene Aliases: AI323757, Flt-1, VEGFR-1, VEGFR1, sFlt1
• Chromosome Location: Chr.5: 147562196 - 147726444 on Build GRCm38
• UniGene ID: Mm.389712
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Flt1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010228.3	NP_034358.2	16, 17	2614
GenBank mRNA	D88689.1	-	16, 17	2611
	L07297.1	-	16, 17	2386
	X78568.1	-	16, 17	2599

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019306, D28498.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
patterning of blood vessels
response to hypoxia
sprouting angiogenesis
monocyte chemotaxis
protein phosphorylation
chemotaxis
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
positive regulation of phospholipase C activity
positive regulation of phosphatidylinositol 3-kinase signaling
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
cellular response to vascular endothelial growth factor stimulus
vascular endothelial growth factor receptor-1 signaling pathway
vascular endothelial growth factor signaling pathway
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of angiogenesis
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
blood vessel morphogenesis
embryonic morphogenesis
positive regulation of hematopoietic progenitor cell differentiation

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding
VEGF-A-activated receptor activity
VEGF-B-activated receptor activity
placental growth factor-activated receptor activity
identical protein binding