s66295

• Gene Symbol: Fyn
• Gene Name: Fyn proto-oncogene
• Gene Aliases: AI448320, AW552119
• Chromosome Location: Chr.10: 39369770 - 39565381 on Build GRCm38
• UniGene ID: Mm.4848
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fyn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001122892.1	NP_001116364.1	12	1767
	NM_001122893.1	NP_001116365.1	13	1846
	NM_008054.2	NP_032080.2	13	1837
GenBank mRNA	AK156584.1	-	13	1848
	AK171646.1	-	13	1839
	BC010554.1	-	12	1448
	BC032149.1	-	12	1482	3602546
	BC092217.1	-	12	1763	6403711
	M27266.1	-	14	1549
	U70324.1	-	13	1550

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012755, XM_006256520, XM_006256522, XM_006256521, FQ231621, and others.

Gene Ontology Categories:

Process(es)

neuron migration
immune system process
protein phosphorylation
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
regulation of cell shape
negative regulation of gene expression
positive regulation of neuron projection development
positive regulation of phosphatidylinositol 3-kinase signaling
phosphorylation
peptidyl-tyrosine phosphorylation
cell differentiation
forebrain development
negative regulation of protein ubiquitination
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
negative regulation of protein catabolic process
myelination
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of neuron apoptotic process
innate immune response
response to ethanol
protein autophosphorylation
dendrite morphogenesis
activated T cell proliferation
T cell receptor signaling pathway
detection of mechanical stimulus involved in sensory perception of pain
cellular response to peptide hormone stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of protein localization to nucleus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
G-protein coupled receptor binding
glycoprotein binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
tubulin binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein complex binding
T cell receptor binding
CD4 receptor binding
CD8 receptor binding
phosphatidylinositol 3-kinase binding
ion channel binding
metal ion binding
ephrin receptor binding
peptide hormone receptor binding
growth factor receptor binding