s66993

• Gene Symbol: Grb2
• Gene Name: growth factor receptor bound protein 2
• Gene Aliases: AA408164, Ash
• Chromosome Location: Chr.11: 115644130 - 115708597 on Build GRCm38
• UniGene ID: Mm.439649
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Grb2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008163.3	NP_032189.1	5	722
GenBank mRNA	AK077750.1	-	4	542
	AK079087.1	-	4	550
	AK148148.1	-	5	687
	AK153557.1	-	4	655
	AK155800.1	-	5	677
	AK166142.1	-	5	676
	AK170845.1	-	4	513
	AK172002.1	-	5	698
	AK212651.1	-	1	47
	AK216513.1	-	1	47
	AK217799.1	-	1	47
	BC052377.1	-	5	722	5696248
	BC085254.1	-	5	558	5343274
	D85748.1	-	3	346
	U07617.1	-	4	471

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_030846, XM_008768457, X62853, D49848, BC091144, and others.

Gene Ontology Categories:

Process(es)

Ras protein signal transduction
aging
insulin receptor signaling pathway
fibroblast growth factor receptor signaling pathway
positive regulation of signal transduction
cell differentiation
positive regulation of actin filament polymerization
receptor internalization
signal transduction in response to DNA damage
regulation of MAPK cascade
anatomical structure formation involved in morphogenesis
protein heterooligomerization
branching involved in labyrinthine layer morphogenesis
cellular response to ionizing radiation
positive regulation of reactive oxygen species metabolic process

Function(s)

phosphotyrosine binding
SH3/SH2 adaptor activity
epidermal growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
SH3 domain binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
identical protein binding
insulin receptor substrate binding
poly(A) RNA binding
ephrin receptor binding
phosphoprotein binding