s67067

• Gene Symbol: Nr3c1
• Gene Name: nuclear receptor subfamily 3, group C, member 1
• Gene Aliases: GR, Grl-1, Grl1
• Chromosome Location: Chr.18: 39410545 - 39519416 on Build GRCm38
• UniGene ID: Mm.129481
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr3c1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008173.3	NP_032199.3	6	1979
GenBank mRNA	AK037733.1	-	6	1860
	AK155200.1	-	8	2061
	AK156323.1	-	8	2055
	BC129912.1	-	7	1957	40111802
	BC129913.1	-	7	1957	40111803
	DQ504162.1	-	6	1963
	HM236293.1	-	7	1939
	X04435.1	-	7	1957
	X13358.1	-	7	1939
	X13359.1	-	7	1942

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012576, XM_008772065, XM_008772066, M14053, AB115420, and others.

Gene Ontology Categories:

Process(es)

regulation of gluconeogenesis
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
glucocorticoid metabolic process
regulation of glucose metabolic process
positive regulation of glutamate secretion
chromatin modification
adrenal gland development
negative regulation of synaptic plasticity
regulation of glucocorticoid biosynthetic process
regulation of cell proliferation
maternal behavior
glucocorticoid receptor signaling pathway
negative regulation of vascular permeability
steroid hormone mediated signaling pathway
glucocorticoid mediated signaling pathway
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
response to arsenic-containing substance
chromatin-mediated maintenance of transcription
mammary gland duct morphogenesis
positive regulation of dendritic spine development
positive regulation of cell growth involved in cardiac muscle cell development
cellular response to steroid hormone stimulus
cellular response to dexamethasone stimulus
negative regulation of glucocorticoid mediated signaling pathway
positive regulation of glucocorticoid receptor signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription coactivator activity
glucocorticoid receptor activity
steroid binding
protein binding
transcription factor binding
zinc ion binding
lipid binding
Hsp70 protein binding
receptor tyrosine kinase binding
heat shock protein binding
protein complex binding
glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity
hormone binding
protein homodimerization activity
sequence-specific DNA binding
metal ion binding
protein heterodimerization activity
protein dimerization activity
Hsp90 protein binding
steroid hormone binding