s6738

• Gene Symbol: HNRNPK
• Gene Name: heterogeneous nuclear ribonucleoprotein K
• Gene Aliases: AUKS, CSBP, HNRPK, TUNP
• Chromosome Location: Chr.9: 83968083 - 83980782 on Build GRCh38
• UniGene ID: Hs.522257
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HNRNPK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001318186.1	NP_001305115.1	15	1381
	NM_001318187.1	NP_001305116.1	15	1381
	NM_001318188.1	NP_001305117.1	16	1453
	NM_002140.4	NP_002131.2	16	1614
	NM_031262.3	NP_112552.1	16	1614
	NM_031263.3	NP_112553.1	16	1453
	XM_005251960.2	XP_005252017.1	16	1432
	XM_005251963.3	XP_005252020.1	15	1394
	XM_005251965.2	XP_005252022.1	15	1352
	XM_011518616.1	XP_011516918.1	15	1394
	XM_017014668.1	XP_016870157.1	16	1432
	XM_017014669.1	XP_016870158.1	15	1352
GenBank mRNA	AB209562.1	-	15	1310
	AB451263.1	-	14	1227
	AB451390.1	-	14	1227
	AK096385.1	-	15	1239
	AK123117.1	-	10	2179
	AK291336.1	-	16	1436
	AK294067.1	-	15	1411
	AK300744.1	-	15	1324
	AK307962.1	-	17	1274
	AY911506.1	-	15	1290
	BC000355.2	-	15	1349	2964383
	BC014980.1	-	16	1420	4906241
	BC025321.1	-	16	1372
	CR456771.1	-	14	1227
	S74678.1	-	15	1334
	X72727.1	-	16	1436

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_057141, XM_006253552, XM_006253554, XM_006253553, XM_006253555, and others.
This siRNA also targets the following transcripts in Mouse: NM_001301341, NM_025279, NM_001301340, NM_001301344, NM_001301345, and others.

Panther Classification:

Molecular Function -

RNA metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mRNA splicing, via spliceosome
ovarian follicle development
kidney development
liver development
transcription from RNA polymerase II promoter
RNA processing
acute-phase response
signal transduction
peripheral nervous system development
aging
gene expression
regulation of low-density lipoprotein particle clearance
response to activity
viral process
protein sumoylation
cerebellum development
hippocampus development
cerebral cortex development
lung development
negative regulation of protein binding
cellular response to insulin stimulus
positive regulation of RNA splicing
camera-type eye development
negative regulation of apoptotic process
positive regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
negative regulation of mRNA splicing, via spliceosome
positive regulation of receptor-mediated endocytosis
thymus development
positive regulation of synaptic transmission
positive regulation of dendritic spine development
cellular response to amino acid stimulus
cellular response to glucose stimulus
regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
cellular response to rapamycin
positive regulation of synapse maturation
cell-cell adhesion
positive regulation of long-term synaptic potentiation
response to salt
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of dendrite extension
cellular response to forskolin
positive regulation of protein localization to cell surface
negative regulation of branching morphogenesis of a nerve

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
single-stranded DNA binding
RNA binding
mRNA 3'-UTR binding
protein binding
lamin binding
transcription factor binding
protein domain specific binding
pre-mRNA 3'-splice site binding
heat shock protein binding
actinin binding
ribonucleoprotein complex binding
poly(A) RNA binding
ATPase binding
cadherin binding involved in cell-cell adhesion
mRNA CDS binding
C-rich single-stranded DNA binding