s67416

• Gene Symbol: Hdac2
• Gene Name: histone deacetylase 2
• Gene Aliases: D10Wsu179e, YAF1, Yy1bp, mRPD3
• Chromosome Location: Chr.10: 36974544 - 37001889 on Build GRCm38
• UniGene ID: Mm.19806
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008229.2	NP_032255.2	9	1169
GenBank mRNA	AB221663.1	-	9	961
	AK135572.1	-	4	475
	BC138517.1	-	9	1141	8861537
	U31758.1	-	9	1129

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001527, U31814, AB209190, AK097376, AK092156, and others.
This siRNA also targets the following transcripts in Rat: NM_053447, AF321130, BC161939.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
maintenance of chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
positive regulation of cell proliferation
epidermal cell differentiation
positive regulation of epithelial to mesenchymal transition
positive regulation of receptor biosynthetic process
negative regulation of neuron projection development
dendrite development
chromatin modification
histone deacetylation
hippocampus development
neuron differentiation
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
circadian regulation of gene expression
odontogenesis of dentin-containing tooth
positive regulation of tyrosine phosphorylation of Stat3 protein
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of oligodendrocyte differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of protein kinase B signaling
cardiac muscle cell development
negative regulation of cardiac muscle cell proliferation
regulation of sarcomere organization
hair follicle placode formation
negative regulation of dendritic spine development
eyelid development in camera-type eye
fungiform papilla formation
cellular response to hydrogen peroxide
histone H3 deacetylation
histone H4 deacetylation
negative regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
negative regulation of peptidyl-lysine acetylation
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
transcription factor binding
hydrolase activity
deacetylase activity
enzyme binding
heat shock protein binding
histone deacetylase activity (H3-K14 specific)
chromatin DNA binding
nucleosomal DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
histone deacetylase activity (H4-K16 specific)
Krueppel-associated box domain binding
sequence-specific DNA binding
poly(A) RNA binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
NF-kappaB binding
NAD-dependent histone deacetylase activity (H3-K18 specific)