s67519

• Gene Symbol: Hhex
• Gene Name: hematopoietically expressed homeobox
• Gene Aliases: Hex, Hex1, Hhex-rs2, Prh, Prhx
• Chromosome Location: Chr.19: 37434841 - 37440731 on Build GRCm38
• UniGene ID: Mm.33896
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hhex
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008245.3	NP_032271.1	2	502
GenBank mRNA	AK014111.1	-	2	501
	AK033664.1	-	2	503
	AK149553.1	-	2	503
	BC057986.1	-	2	489	5124938

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_024385, BC088135, D86383.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
in utero embryonic development
liver development
morphogenesis of an epithelium
myeloid leukocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
mRNA export from nucleus
signal transduction
Notch signaling pathway
multicellular organism development
endoderm development
cell proliferation
organ morphogenesis
anterior/posterior pattern specification
Wnt signaling pathway
negative regulation of angiogenesis
poly(A)+ mRNA export from nucleus
interkinetic nuclear migration
hemopoiesis
cell differentiation
positive regulation of Wnt signaling pathway
B cell differentiation
thyroid gland development
forebrain development
negative regulation of vascular endothelial growth factor receptor signaling pathway
pancreas development
protein localization to nucleus
embryonic heart tube development
multicellular organism growth
regulation of cell proliferation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic organ development
tissue morphogenesis
forebrain morphogenesis
primary lung bud formation
common bile duct development
gall bladder development
hepatic duct development
hepatoblast differentiation
hepatocyte differentiation
DNA conformation change
primitive streak formation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
eukaryotic initiation factor 4E binding
DNA binding, bending
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
repressing transcription factor binding
HMG box domain binding