s676 Validated

Gene Symbol:

DVL3 DVL1

Gene Name:

dishevelled segment polarity protein 3

dishevelled segment polarity protein 1

Gene Aliases:

DRS3

DRS2, DVL, DVL1L1, DVL1P1

Chromosome Location:

Chr.3: 184155311 - 184173614 on Build GRCh38

Chromosome Location:

Chr.1: 1335278 - 1349142 on Build GRCh38

UniGene ID:

Hs.388116

Hs.731450

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: DVL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004423.3	NP_004414.3	7	894
	XM_005247172.2	XP_005247229.1	7	1079
	XM_011512513.2	XP_011510815.1	4	682
GenBank mRNA	AF006013.1	-	7	765
	AK093469.1	-	7	886
	AK304686.1	-	8	846
	AL110278.1	-	3	536
	BC018289.1	-	5	430
	BC032459.1	-	7	822	5200610
	D86963.1	-	7	894
	U75651.1	-	7	1147

Gene Symbol: DVL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	U46461.1	-	7	904

More Information

Matching Taqman Gene Expression Assay:

Hs00610263_m1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
outflow tract septum morphogenesis
Wnt signaling pathway
intracellular signal transduction
non-canonical Wnt signaling pathway
non-canonical Wnt signaling pathway via JNK cascade
response to drug
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of transcription, DNA-templated
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
regulation of cellular protein localization
beta-catenin destruction complex disassembly

Function(s)

protease binding
receptor binding
frizzled binding
protein binding
beta-catenin binding
protein binding, bridging
protein heterodimerization activity
Rac GTPase binding