s68378

• Gene Symbol: Irf1
• Gene Name: interferon regulatory factor 1
• Gene Aliases: AU020929, Irf-1
• Chromosome Location: Chr.11: 53770014 - 53778374 on Build GRCm38
• UniGene ID: Mm.105218
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Irf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001159393.1	NP_001152865.1	2	319
	NM_001159396.1	NP_001152868.1	2	274
	NM_008390.2	NP_032416.1	2	319
GenBank mRNA	AK152005.1	-	2	283
	AK152104.1	-	2	282
	AK152193.1	-	2	283
	AK153514.1	-	2	283
	AK155983.1	-	2	283
	AK157347.1	-	2	283
	BC003821.1	-	2	252	3600525
	BY266109.1	-	2	320
	BY328342.1	-	2	277
	CT010234.1	-	1	50
	M21065.1	-	2	255

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002198, BT019755, X14454, BC009483, AB103081, and others.
This siRNA also targets the following transcripts in Rat: NM_012591, BC076382, M34253.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

immune system process
regulation of adaptive immune response
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
cell cycle arrest
I-kappaB kinase/NF-kappaB signaling
regulation of gene expression
positive regulation of cell death
positive regulation of type I interferon production
positive regulation of interferon-beta production
positive regulation of natural killer cell differentiation
regulation of MyD88-dependent toll-like receptor signaling pathway
cellular response to interferon-beta
negative regulation of tyrosine phosphorylation of Stat1 protein
CD8-positive, alpha-beta T cell differentiation
positive regulation of interleukin-12 biosynthetic process
innate immune response
regulation of innate immune response
negative regulation of regulatory T cell differentiation
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
interferon-gamma-mediated signaling pathway
response to growth hormone
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

regulatory region DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding