s68457

• Gene Symbol: Itgb1bp1
• Gene Name: integrin beta 1 binding protein 1
• Gene Aliases: AI449260, AU019480, Icap1
• Chromosome Location: Chr.12: 21267246 - 21286279 on Build GRCm38
• UniGene ID: Mm.273333
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Itgb1bp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008403.4	NP_032429.1	2	241
GenBank mRNA	AJ001373.1	-	2	223
	AK002786.1	-	2	198
	AK004172.1	-	2	197
	AK007635.1	-	2	199
	AK075577.1	-	2	242
	AK089937.1	-	2	355
	AK147929.1	-	2	190
	BC021151.1	-	2	380
	BC028772.1	-	1	77	1230640

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106719, XM_006239979, XM_006239981, XM_006239980, BC169104, and others.

Gene Ontology Categories:

Process(es)

angiogenesis
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of protein kinase activity
negative regulation of cell adhesion involved in substrate-bound cell migration
cell adhesion
cell-matrix adhesion
Notch signaling pathway
integrin-mediated signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of endothelial cell migration
negative regulation of fibroblast migration
protein transport
cell differentiation
regulation of cell adhesion
biomineral tissue development
negative regulation of protein binding
activation of protein kinase B activity
integrin activation
regulation of cell adhesion mediated by integrin
tube formation
cellular response to vascular endothelial growth factor stimulus
regulation of GTPase activity
receptor clustering
cellular response to fibroblast growth factor stimulus
positive regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
regulation of blood vessel size
myoblast migration
positive regulation of stress fiber assembly
positive regulation of cell division
positive regulation of focal adhesion assembly
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
negative regulation of cell migration involved in sprouting angiogenesis
positive regulation of protein targeting to membrane
negative regulation of protein targeting to membrane
negative regulation of substrate adhesion-dependent cell spreading
regulation of integrin-mediated signaling pathway

Function(s)

GDP-dissociation inhibitor activity
integrin binding
protein binding
protein C-terminus binding
protein transporter activity
kinase binding
protein kinase binding
protein complex binding