s70502

• Gene Symbol: Nf2
• Gene Name: neurofibromatosis 2
• Gene Aliases: merlin
• Chromosome Location: Chr.11: 4757650 - 4849544 on Build GRCm38
• UniGene ID: Mm.297109
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nf2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001252250.1	NP_001239179.1	2	788
	NM_001252251.1	NP_001239180.1	2	788
	NM_001252252.1	NP_001239181.1	2	788
	NM_001252253.1	NP_001239182.1	2	253
	NM_010898.4	NP_035028.2	2	788
GenBank mRNA	AK017343.1	-	2	254
	AK045998.1	-	2	610
	AK185632.1	-	1	76
	AK203557.1	-	1	76
	AK213371.1	-	1	76
	BC005442.1	-	2	654	3496053
	CN715904.1	-	2	346
	L22987.1	-	2	246
	L22988.1	-	2	246
	L22989.1	-	2	246
	L27090.1	-	2	239
	L27105.1	-	2	239
	L28176.1	-	2	546
	X74671.1	-	2	805

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_181832, NM_181833, NM_181829, NM_016418, NM_000268, and others.
This siRNA also targets the following transcripts in Rat: NM_013193, XM_006251191, XM_006251188, U61772.

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

mesoderm formation
negative regulation of protein kinase activity
ectoderm development
brain development
negative regulation of DNA replication
negative regulation of cell proliferation
Schwann cell proliferation
regulation of gliogenesis
hippocampus development
negative regulation of cell-cell adhesion
actin cytoskeleton organization
negative regulation of cell growth
regulation of protein stability
regulation of hippo signaling
regulation of cell proliferation
odontogenesis of dentin-containing tooth
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of MAPK cascade
cell-cell junction organization
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
regulation of neurogenesis
positive regulation of stress fiber assembly
lens fiber cell differentiation
regulation of stem cell proliferation
regulation of protein localization to nucleus
regulation of neural precursor cell proliferation

Function(s)

actin binding
integrin binding
protein binding
beta-catenin binding
cytoskeletal protein binding
protein domain specific binding