s71333

• Gene Symbol: Furin
• Gene Name: furin (paired basic amino acid cleaving enzyme)
• Gene Aliases: 9130404I01Rik, Fur, PACE, Pcsk3, SPC1
• Chromosome Location: Chr.7: 80389194 - 80405445 on Build GRCm38
• UniGene ID: Mm.5241
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Furin
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001081454.1	NP_001074923.1	2, 3	455
	NM_011046.2	NP_035176.1	2, 3	575
GenBank mRNA	BC048234.1	-	1, 2	282	6492009
	L26489.1	-	2, 3	575
	X54056.1	-	1, 2	278

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019331, XM_008759556, XM_008759555, X55660.

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

signal peptide processing
proteolysis
cell proliferation
regulation of signal transduction
negative regulation of endopeptidase activity
protein processing
peptide hormone processing
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of low-density lipoprotein particle receptor catabolic process
nerve growth factor production
negative regulation of transforming growth factor beta1 production
secretion by cell
regulation of protein catabolic process
peptide biosynthetic process
regulation of low-density lipoprotein particle receptor biosynthetic process
regulation of endopeptidase activity

Function(s)

protease binding
endopeptidase activity
serine-type endopeptidase activity
serine-type endopeptidase inhibitor activity
protein binding
peptidase activity
serine-type peptidase activity
hydrolase activity
peptide binding
metal ion binding
nerve growth factor binding