s7212 Validated

• Gene Symbol: IGF1R
• Gene Name: insulin like growth factor 1 receptor
• Gene Aliases: CD221, IGFIR, IGFR, JTK13
• Chromosome Location: Chr.15: 98648539 - 98964530 on Build GRCh38
• UniGene ID: Hs.643120
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IGF1R
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000875.4	NP_000866.1	18	4482
	NM_001291858.1	NP_001278787.1	18	4479
	XM_011521516.2	XP_011519818.1	17	2932
	XM_011521517.2	XP_011519819.1	14	2345
	XM_017022136.1	XP_016877625.1	18	3985
	XM_017022137.1	XP_016877626.1	18	3985
	XM_017022138.1	XP_016877627.1	18	3982
	XM_017022139.1	XP_016877628.1	18	3423
GenBank mRNA	AB425196.1	-	18	3965
	BC113610.1	-	18	3471	8322662
	BC113612.1	-	18	3471	8322664
	BC143721.1	-	18	3468	9052235
	X04434.1	-	18	3484

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010513, BC138869, AK137220, BC138868, AK155884, and others.

Matching Taqman Gene Expression Assay:

Hs00609566_m1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

immune response
signal transduction
positive regulation of cell proliferation
insulin receptor signaling pathway
phosphatidylinositol 3-kinase signaling
positive regulation of cell migration
peptidyl-tyrosine autophosphorylation
negative regulation of apoptotic process
positive regulation of DNA replication
regulation of JNK cascade
protein autophosphorylation
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
protein tetramerization
inactivation of MAPKK activity

Function(s)

protein tyrosine kinase activity
insulin-like growth factor-activated receptor activity
insulin receptor binding
protein binding
insulin-like growth factor binding
ATP binding
insulin-like growth factor I binding
identical protein binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding