s7251

• Gene Symbol: RBPJ
• Gene Name: recombination signal binding protein for immunoglobulin kappa J region
• Gene Aliases: AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
• Chromosome Location: Chr.4: 26163489 - 26435131 on Build GRCh38
• UniGene ID: Hs.479396
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RBPJ
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005349.3	NP_005340.2	3, 4	342
	NM_015874.4	NP_056958.3	2, 3	289
	NM_203283.2	NP_976028.1	2, 3	226
	NM_203284.2	NP_976029.1	3, 4	472
	XM_005248161.3	XP_005248218.1	3, 4	356
	XM_011513840.2	XP_011512142.1	3, 4	748
	XM_017008170.1	XP_016863659.1	2, 3	145
	XM_017008171.1	XP_016863660.1	2, 3	124
	XM_017008172.1	XP_016863661.1	3, 4	287
	XM_017008173.1	XP_016863662.1	3, 4	565
	XM_017008174.1	XP_016863663.1	3, 4	381
	XM_017008175.1	XP_016863664.1	3, 4	297
GenBank mRNA	AK302230.1	-	2, 3	79
	AK303244.1	-	2, 3	138
	AK311419.1	-	2, 3	125
	BC020780.1	-	2, 3	226	4718839
	BC064976.1	-	3, 4	247	6152924
	BE269143.1	-	3, 4	252
	BM472788.1	-		296
	BM555733.1	-	3, 4	450
	BQ216033.1	-	2, 3	270
	DC361185.1	-	2, 3	289
	DC389691.1	-	3, 4	472
	L07872.1	-	2, 3	184
	L07874.1	-	2, 3	301
	L07875.1	-	3, 4	364
	L07876.1	-	2, 3	229

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106631, XM_008770190, XM_008770193, XM_008770191, XM_006237737, and others.
This siRNA also targets the following transcripts in Mouse: NM_009035, NM_001080928, NM_001080927, NM_001277116, BY107008, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
somitogenesis
epithelial to mesenchymal transition
blood vessel remodeling
inflammatory response to antigenic stimulus
secondary heart field specification
outflow tract morphogenesis
endocardium morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
cardiac left ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
DNA recombination
transcription initiation from RNA polymerase II promoter
humoral immune response
Notch signaling pathway
positive regulation of transcription of Notch receptor target
negative regulation of cell proliferation
auditory receptor cell fate commitment
epidermal cell fate specification
pituitary gland development
B cell differentiation
keratinocyte differentiation
negative regulation of ossification
positive regulation of BMP signaling pathway
somatic stem cell population maintenance
dorsal aorta morphogenesis
atrioventricular canal development
defense response to bacterium
myeloid dendritic cell differentiation
negative regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of cell differentiation
sebaceous gland development
hair follicle maturation
positive regulation of cardiac muscle cell proliferation
Clara cell differentiation
labyrinthine layer blood vessel development
arterial endothelial cell fate commitment
Notch signaling involved in heart development
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
blood vessel lumenization
interleukin-4 secretion
blood vessel endothelial cell fate specification
positive regulation of ERBB signaling pathway
positive regulation of ephrin receptor signaling pathway
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
positive regulation of cell proliferation involved in heart morphogenesis

Function(s)

recombinase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
sequence-specific DNA binding
protein N-terminus binding