s74176

• Gene Symbol: Sox2
• Gene Name: SRY (sex determining region Y)-box 2
• Gene Aliases: Sox-2, lcc, ysb
• Chromosome Location: Chr.3: 34650005 - 34652461 on Build GRCm38
• UniGene ID: Mm.65396
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Sox2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011443.3	NP_035573.3	1	2148
GenBank mRNA	AK131933.1	-	1	1583
	BC057574.1	-	2	1986	6413283
	U31967.1	-	3	1976

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003106, CN430685.
This siRNA also targets the following transcripts in Rat: NM_001109181.

Panther Classification:

Molecular Function -

HMG box transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
cell fate specification
endodermal cell fate specification
positive regulation of neuroblast proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell cycle arrest
multicellular organism development
sensory perception of sound
response to organic substance
regulation of gene expression
stem cell population maintenance
forebrain neuron differentiation
adenohypophysis development
cerebral cortex development
positive regulation of cell-cell adhesion
negative regulation of Wnt signaling pathway
male genitalia development
positive regulation of epithelial cell differentiation
olfactory placode formation
response to retinoic acid
somatic stem cell population maintenance
inner ear morphogenesis
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
tongue development
cell fate commitment
negative regulation of cell differentiation
positive regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of neuron differentiation
negative regulation of osteoblast differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
pigment biosynthetic process
lung alveolus development
embryonic organ development
anatomical structure formation involved in morphogenesis
neuron fate commitment
diencephalon morphogenesis
stem cell differentiation
negative regulation of epithelial cell proliferation
regulation of neurogenesis
detection of mechanical stimulus involved in sensory perception of sound
detection of mechanical stimulus involved in equilibrioception
retina morphogenesis in camera-type eye
lens induction in camera-type eye
epithelial tube branching involved in lung morphogenesis
response to growth factor
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding
miRNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity