s74383

• Gene Symbol: Src
• Gene Name: Rous sarcoma oncogene
• Gene Aliases: AW259666, pp60c-src
• Chromosome Location: Chr.2: 157423901 - 157471838 on Build GRCm38
• UniGene ID: Mm.22845
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Src
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025395.2	NP_001020566.1	6, 7	830
	NM_009271.3	NP_033297.2	7, 8	848
GenBank mRNA	AK146056.1	-		777
	AK190301.1	-	1, 2	54
	BC039953.1	-	6, 7	840	4192014
	CX218263.1	-	3, 4	329
	M17031.1	-	4, 5	464

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031977, XM_008762389, XM_008762388, XM_008762387, DQ120510, and others.

Gene Ontology Categories:

Process(es)

immune system process
protein phosphorylation
cell cycle
cell adhesion
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
cell proliferation
positive regulation of gene expression
regulation of epithelial cell migration
positive regulation of epithelial cell migration
positive regulation of glucose metabolic process
positive regulation of smooth muscle cell migration
phosphorylation
cell migration
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
cell differentiation
forebrain development
positive regulation of protein autophosphorylation
activation of protein kinase B activity
negative regulation of protein homooligomerization
regulation of intracellular estrogen receptor signaling pathway
adherens junction organization
substrate adhesion-dependent cell spreading
cellular response to reactive oxygen species
intracellular signal transduction
osteoclast development
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of apoptotic process
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of protein binding
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
transcytosis
innate immune response
bone resorption
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell adhesion
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of insulin receptor signaling pathway
protein autophosphorylation
neurotrophin TRK receptor signaling pathway
oogenesis
positive regulation of cytokine secretion
progesterone receptor signaling pathway
positive regulation of protein transport
regulation of cell cycle
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of mitochondrial depolarization
uterus development
branching involved in mammary gland duct morphogenesis
regulation of cell projection assembly
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to peptide hormone stimulus
cellular response to progesterone stimulus
cellular response to fluid shear stress
cellular response to transforming growth factor beta stimulus
positive regulation of podosome assembly
angiotensin-activated signaling pathway involved in heart process
positive regulation of canonical Wnt signaling pathway
positive regulation of intracellular signal transduction
positive regulation of lamellipodium morphogenesis
positive regulation of DNA biosynthetic process
regulation of early endosome to late endosome transport
negative regulation of anoikis
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway
regulation of caveolin-mediated endocytosis

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
receptor binding
insulin receptor binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
protein kinase binding
protein domain specific binding
heme binding
estrogen receptor binding
protein complex binding
SH2 domain binding
ion channel binding
ephrin receptor binding
cell adhesion molecule binding
phosphoprotein binding
hormone receptor binding
growth factor receptor binding
scaffold protein binding