s74389

• Gene Symbol: Srebf2
• Gene Name: sterol regulatory element binding factor 2
• Gene Aliases: AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc
• Chromosome Location: Chr.15: 82147269 - 82205379 on Build GRCm38
• UniGene ID: Mm.38016
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Srebf2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_033218.1	NP_150087.1	10	2006
GenBank mRNA	AK155857.1	-	11	1954
	AK172219.1	-	10	2013
	BQ963055.1	-	1	61

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001033694, XM_006242079, BC101902.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cellular response to starvation
response to hormone
positive regulation of cholesterol storage
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
E-box binding