s74460

• Gene Symbol: Stat5b
• Gene Name: signal transducer and activator of transcription 5B
• Gene Aliases: -
• Chromosome Location: Chr.11: 100780731 - 100859004 on Build GRCm38
• UniGene ID: Mm.34064
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Stat5b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113563.1	NP_001107035.1	2, 3	333
	NM_011489.3	NP_035619.3	2, 3	665
GenBank mRNA	AK045531.1	-	2, 3	476
	AK150098.1	-	2, 3	302
	AK154014.1	-	2, 3	665
	AK154664.1	-	2, 3	299
	AY040231.1	-	2, 3	619
	AY042906.1	-	2, 3	619
	AY044901.1	-	2, 3	619
	AY044902.1	-	2, 3	619
	AY044903.1	-	2, 3	619
	BC024319.1	-	2, 3	289	4237132
	U21110.2	-	2, 3	619
	Z48539.1	-	2, 3	233

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022380, X97541, X91988.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

allantoin metabolic process
luteinization
natural killer cell differentiation
liver development
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
acute-phase response
signal transduction
JAK-STAT cascade
sex differentiation
female pregnancy
lactation
positive regulation of cell proliferation
regulation of steroid metabolic process
cytokine-mediated signaling pathway
taurine metabolic process
lipid storage
regulation of cell adhesion
regulation of epithelial cell differentiation
response to estradiol
response to lipopolysaccharide
positive regulation of natural killer cell proliferation
positive regulation of natural killer cell differentiation
cellular response to hormone stimulus
T cell differentiation in thymus
prolactin signaling pathway
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of activated T cell proliferation
progesterone metabolic process
T cell homeostasis
negative regulation of apoptotic process
response to peptide hormone
positive regulation of interleukin-2 biosynthetic process
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of lymphocyte differentiation
negative regulation of erythrocyte differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
positive regulation of natural killer cell mediated cytotoxicity
creatinine metabolic process
development of secondary female sexual characteristics
development of secondary male sexual characteristics
Peyer's patch development
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of cellular component movement
JAK-STAT cascade involved in growth hormone signaling pathway
response to interleukin-2
response to interleukin-4
response to interleukin-15
cellular response to growth factor stimulus
cellular response to epidermal growth factor stimulus
mast cell migration

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
protein binding
protein phosphatase binding
glucocorticoid receptor binding
sequence-specific DNA binding
protein dimerization activity