s7449

• Gene Symbol: INS
• Gene Name: insulin
• Gene Aliases: IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10
• Chromosome Location: Chr.11: 2159779 - 2161209 on Build GRCh38
• UniGene ID: Hs.272259
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: INS
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000207.2	NP_000198.1	3	344
	NM_001185097.1	NP_001172026.1	3	370
	NM_001185098.1	NP_001172027.1	2	523
	NM_001291897.1	NP_001278826.1	3	404
GenBank mRNA	AY899304.1	-	3	340
	BC005255.1	-	3	344	3950204
	BM510347.1	-	3	365
	BM510748.1	-	3	348
	BP322143.1	-	2	523
	BT006808.1	-	2	285
	DQ778082.1	-	2	249
	JF909299.1	-	2	238
	JQ951950.1	-	3	329
	X70508.1	-	3	329

More Information

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
negative regulation of acute inflammatory response
glucose metabolic process
regulation of transcription, DNA-templated
regulation of cellular amino acid metabolic process
ER to Golgi vesicle-mediated transport
acute-phase response
G-protein coupled receptor signaling pathway
cell-cell signaling
positive regulation of cell proliferation
insulin receptor signaling pathway
positive regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
glucose transport
regulation of transmembrane transporter activity
positive regulation of cell growth
positive regulation of cell migration
positive regulation of protein autophosphorylation
activation of protein kinase B activity
positive regulation of cellular protein metabolic process
negative regulation of protein oligomerization
regulation of protein localization
negative regulation of NAD(P)H oxidase activity
wound healing
negative regulation of protein catabolic process
glucose homeostasis
positive regulation of MAPK cascade
cellular protein metabolic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
negative regulation of gluconeogenesis
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
negative regulation of glycogen catabolic process
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
negative regulation of proteolysis
negative regulation of vasodilation
positive regulation of vasodilation
negative regulation of fatty acid metabolic process
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
alpha-beta T cell activation
positive regulation of lipid biosynthetic process
regulation of protein secretion
negative regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipid catabolic process
positive regulation of nitric-oxide synthase activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
fatty acid homeostasis
negative regulation of respiratory burst involved in inflammatory response
positive regulation of respiratory burst
positive regulation of peptide hormone secretion
positive regulation of brown fat cell differentiation
positive regulation of protein localization to nucleus
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of feeding behavior

Function(s)

protease binding
insulin receptor binding
insulin-like growth factor receptor binding
hormone activity
protein binding
identical protein binding