s7461

• Gene Symbol: INPP5D
• Gene Name: inositol polyphosphate-5-phosphatase D
• Gene Aliases: SHIP, SHIP-1, SHIP1, SIP-145, hp51CN, p150Ship
• Chromosome Location: Chr.2: 233059967 - 233207903 on Build GRCh38
• UniGene ID: Hs.262886
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: INPP5D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001017915.2	NP_001017915.1	17	2463
	NM_005541.4	NP_005532.2	17	2460
	XM_017004004.1	XP_016859493.1	17	2039
GenBank mRNA	BC099920.1	-	17	2071	6304992
	BC113580.1	-	17	2008	8322632
	BC113582.1	-	17	2008	8322634
	U50040.1	-	12	1328
	U50041.1	-	17	2072
	U53470.1	-	17	2081
	U57650.1	-	17	2460
	U84400.1	-	17	2032
	X98429.1	-	17	2088

More Information

Gene Ontology Categories:

Process(es)

phosphatidylinositol biosynthetic process
phosphate-containing compound metabolic process
apoptotic process
signal transduction
determination of adult lifespan
negative regulation of signal transduction
immunoglobulin mediated immune response
negative regulation of B cell proliferation
intracellular signal transduction
positive regulation of apoptotic process
inositol phosphate metabolic process
negative regulation of interleukin-6 biosynthetic process
positive regulation of B cell differentiation
positive regulation of erythrocyte differentiation
negative regulation of monocyte differentiation
negative regulation of neutrophil differentiation
negative regulation of osteoclast differentiation
negative regulation of bone resorption
phosphatidylinositol dephosphorylation
negative regulation of immune response
T cell receptor signaling pathway
leukocyte migration

Function(s)

inositol-polyphosphate 5-phosphatase activity
protein binding
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
SH3 domain binding
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
PTB domain binding
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity