s74734

• Gene Symbol: Tap2
• Gene Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Gene Aliases: ABC18, AI462429, APT2, Abcb3, Ham-2, Ham2, MTP2, PSF2, RING11, Tap-2, Y1, jas
• Chromosome Location: Chr.17: 34204085 - 34216321 on Build GRCm38
• UniGene ID: Mm.14814
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tap2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011530.3	NP_035660.3	2	562
GenBank mRNA	AK020022.1	-	2	475
	AK079667.1	-	2	475
	AK151657.1	-	2	495
	AK159200.1	-	2	528
	AK161091.1	-	2	476
	BC005578.1	-	2	462	3968225
	BC051257.1	-	2	475	6530488
	BC057668.1	-	2	848
	CT010387.1	-	1	409
	M90459.1	-	1	409
	U60092.1	-	1	409

More Information

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
response to molecule of bacterial origin
immune system process
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
positive regulation of antigen processing and presentation of peptide antigen via MHC class I
protein complex assembly
transport
protein transport
peptide transport
intracellular transport of viral protein in host cell
antigen processing and presentation of endogenous peptide antigen via MHC class I
protection from natural killer cell mediated cytotoxicity
cytosol to ER transport
peptide antigen transport
transmembrane transport

Function(s)

nucleotide binding
protein binding
ATP binding
peptide transporter activity
peptide antigen-transporting ATPase activity
peptide-transporting ATPase activity
ATPase activity
MHC class Ib protein binding
MHC protein binding
MHC class I protein binding
peptide antigen binding
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
ADP binding
TAP1 binding
TAP2 binding
tapasin binding
protein heterodimerization activity