s75203

• Gene Symbol: Tlr1
• Gene Name: toll-like receptor 1
• Gene Aliases: -
• Chromosome Location: Chr.5: 64924680 - 64933589 on Build GRCm38
• UniGene ID: Mm.273024
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tlr1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001276445.1	NP_001263374.1	4	949
	NM_030682.2	NP_109607.1	3	649
GenBank mRNA	AF316985.1	-	1	501
	AK143721.1	-	4	953
	AK172870.1	-	1	277
	AY009154.1	-	3	649
	BC141319.1	-	3	711	9055931
	BC141321.1	-	3	711	9055933

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001172120.

Gene Ontology Categories:

Process(es)

microglial cell activation
toll-like receptor signaling pathway
immune system process
MyD88-dependent toll-like receptor signaling pathway
defense response
inflammatory response
immune response
signal transduction
activation of NF-kappaB-inducing kinase activity
response to bacterial lipoprotein
toll-like receptor 1 signaling pathway
macrophage activation
detection of triacyl bacterial lipopeptide
positive regulation of tumor necrosis factor biosynthetic process
innate immune response
positive regulation of interleukin-6 biosynthetic process
regulation of cytokine secretion
cellular response to triacyl bacterial lipopeptide

Function(s)

transmembrane signaling receptor activity
triacyl lipopeptide binding
protein heterodimerization activity
lipopeptide binding