s75429

• Gene Symbol: Traf3
• Gene Name: TNF receptor-associated factor 3
• Gene Aliases: AI528849, CAP-1, CD40bp, CRAF1, LAP1, T-BAM, amn
• Chromosome Location: Chr.12: 111166370 - 111267155 on Build GRCm38
• UniGene ID: Mm.27431
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Traf3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001286122.1	NP_001273051.1	6, 7	907
	NM_011632.3	NP_035762.2	8, 9	1093
GenBank mRNA	AK147304.1	-	6, 7	835
	AK147362.1	-	6, 7	908
	AK148231.1	-	2, 3	249
	BC137634.1	-	7, 8	808	8860653
	BC137635.1	-	7, 8	808	8860654
	U21050.1	-	8, 9	912

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108724, XM_006240596.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of cytokine production
toll-like receptor signaling pathway
immune system process
apoptotic process
signal transduction
Toll signaling pathway
protein ubiquitination
regulation of proteolysis
negative regulation of NF-kappaB transcription factor activity
regulation of interferon-beta production
tumor necrosis factor-mediated signaling pathway
regulation of apoptotic process
innate immune response
regulation of defense response to virus

Function(s)

ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
protein kinase binding
ubiquitin protein ligase binding
thioesterase binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity