s761 Validated

• Gene Symbol: TBK1
• Gene Name: TANK binding kinase 1
• Gene Aliases: FTDALS4, NAK, T2K
• Chromosome Location: Chr.12: 64452060 - 64502119 on Build GRCh38
• UniGene ID: Hs.505874
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TBK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013254.3	NP_037386.1	15, 16	1881
	XM_005268809.1	XP_005268866.1	15, 16	1959
	XM_005268810.1	XP_005268867.1	15, 16	1941
GenBank mRNA	AF174536.1	-	14, 15	1722
	AF191838.1	-	15, 16	1784
	AK002192.1	-	7, 8	707
	AK291039.1	-	15, 16	1826
	AK303683.1	-	10, 11	1098
	BC034950.2	-	15, 16	1821	4824988

More Information

Matching Taqman Gene Expression Assay:

Hs00179410_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

inflammatory response
I-kappaB kinase/NF-kappaB signaling
response to virus
negative regulation of gene expression
peptidyl-serine phosphorylation
negative regulation of type I interferon production
positive regulation of type I interferon production
type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of peptidyl-serine phosphorylation
TRIF-dependent toll-like receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
dendritic cell proliferation
innate immune response
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
defense response to Gram-positive bacterium
defense response to virus
regulation of neuron death
positive regulation of xenophagy

Function(s)

nucleic acid binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
phosphoprotein binding