s77695

• Gene Symbol: Prmt5
• Gene Name: protein arginine N-methyltransferase 5
• Gene Aliases: Jbp1, Skb1
• Chromosome Location: Chr.14: 54507182 - 54517470 on Build GRCm38
• UniGene ID: Mm.196585
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prmt5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013768.3	NP_038796.2	3	361
GenBank mRNA	AF167573.1	-	3	229
	AK076346.1	-	3	252
	AK084106.1	-	2	667
	AK132414.1	-	3	253
	AK165165.1	-	3	279
	AK186126.1	-	2	81
	BC023905.1	-	3	308	5321370

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_006109, NM_001039619, AK315500, CR456741, AF167572, and others.
This siRNA also targets the following transcripts in Rat: NM_001108867, CO573950, CB814013.

Panther Classification:

Molecular Function -

protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
spliceosomal snRNP assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
protein methylation
chromatin modification
peptidyl-arginine methylation
peptidyl-arginine methylation, to symmetrical-dimethyl arginine
methylation
circadian regulation of gene expression
histone arginine methylation
peptidyl-arginine N-methylation
endothelial cell activation
histone H4-R3 methylation
regulation of DNA methylation
negative regulation of cell differentiation
rhythmic process
positive regulation of oligodendrocyte differentiation
regulation of ERK1 and ERK2 cascade

Function(s)

rRNA (adenine-N6,N6-)-dimethyltransferase activity
core promoter sequence-specific DNA binding
chromatin binding
transcription corepressor activity
protein C-terminal carboxyl O-methyltransferase activity
tRNA (guanine-N2-)-methyltransferase activity
protein binding
methyltransferase activity
C-methyltransferase activity
N-methyltransferase activity
O-methyltransferase activity
S-methyltransferase activity
RNA methyltransferase activity
mRNA methyltransferase activity
tRNA methyltransferase activity
protein methyltransferase activity
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
histone-arginine N-methyltransferase activity
rRNA methyltransferase activity
rRNA (uridine-2'-O-)-methyltransferase activity
rRNA (adenine-N6-)-methyltransferase activity
DNA-methyltransferase activity
tRNA (guanine-N1-)-methyltransferase activity
rRNA (cytosine-C5-)-methyltransferase activity
selenocysteine methyltransferase activity
arginine N-methyltransferase activity
protein-arginine N-methyltransferase activity
lysine N-methyltransferase activity
protein-lysine N-methyltransferase activity
tRNA (uracil) methyltransferase activity
tRNA (guanine) methyltransferase activity
tRNA (adenine) methyltransferase activity
tRNA (cytosine) methyltransferase activity
tRNA (cytosine-5-)-methyltransferase activity
tRNA (adenine-N1-)-methyltransferase activity
rRNA (adenine) methyltransferase activity
rRNA (cytosine) methyltransferase activity
rRNA (guanine) methyltransferase activity
rRNA (uridine) methyltransferase activity
transferase activity
protein C-terminal leucine carboxyl O-methyltransferase activity
1-phenanthrol methyltransferase activity
protein-arginine N5-methyltransferase activity
methylarsonite methyltransferase activity
protein complex binding
dimethylarsinite methyltransferase activity
4,5-dihydroxybenzo(a)pyrene methyltransferase activity
1-hydroxypyrene methyltransferase activity
1-hydroxy-6-methoxypyrene methyltransferase activity
protein-arginine omega-N symmetric methyltransferase activity
ribonucleoprotein complex binding
demethylmenaquinone methyltransferase activity
cobalt-precorrin-6B C5-methyltransferase activity
cobalt-precorrin-7 C15-methyltransferase activity
cobalt-precorrin-5B C1-methyltransferase activity
cobalt-precorrin-3 C17-methyltransferase activity
dimethylamine methyltransferase activity
hydroxyneurosporene-O-methyltransferase activity
tRNA (adenine-57, 58-N(1)-) methyltransferase activity
methylamine-specific methylcobalamin:coenzyme M methyltransferase activity
trimethylamine methyltransferase activity
methanol-specific methylcobalamin:coenzyme M methyltransferase activity
monomethylamine methyltransferase activity
protein heterodimerization activity
P-methyltransferase activity
Se-methyltransferase activity
2-phytyl-1,4-naphthoquinone methyltransferase activity
tRNA (uracil-2'-O-)-methyltransferase activity
tRNA (cytosine-2'-O-)-methyltransferase activity
phosphomethylethanolamine N-methyltransferase activity
tRNA (cytosine-3-)-methyltransferase activity
rRNA (cytosine-2'-O-)-methyltransferase activity
rRNA (cytosine-N4-)-methyltransferase activity
trihydroxyferuloyl spermidine O-methyltransferase activity