s819 Validated

• Gene Symbol: A2M
• Gene Name: alpha-2-macroglobulin
• Gene Aliases: A2MD, CPAMD5, FWP007, S863-7
• Chromosome Location: Chr.12: 9067708 - 9115962 on Build GRCh38
• UniGene ID: Hs.212838
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: A2M
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000014.4	NP_000005.2	3	477
	XM_006719056.2	XP_006719119.1	3	455
GenBank mRNA	AB209614.2	-	3	388
	AK312482.1	-	3	378
	AY591530.1	-	3	442
	BC026246.1	-	3	433
	BC040071.1	-	3	416	6056126
	CR749334.1	-	3	435
	M11313.1	-	3	407

More Information

Matching Taqman Gene Expression Assay:

Hs00163474_m1

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of complement activation, lectin pathway
platelet degranulation
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
extracellular matrix disassembly
positive regulation of GTPase activity
stem cell differentiation
regulation of small GTPase mediated signal transduction

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
GTPase activator activity
receptor binding
protein binding
growth factor binding
enzyme binding
interleukin-8 binding
interleukin-1 binding
tumor necrosis factor binding
calcium-dependent protein binding