s847

• Gene Symbol: ABCA1
• Gene Name: ATP binding cassette subfamily A member 1
• Gene Aliases: ABC-1, ABC1, CERP, HDLDT1, TGD
• Chromosome Location: Chr.9: 104781002 - 104928246 on Build GRCh38
• UniGene ID: Hs.659274
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ABCA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005502.3	NP_005493.2	24, 25	3942
	XM_011518341.2	XP_011516643.1	25, 26	3926
GenBank mRNA	AB055982.1	-	23, 24	3538
	AB445477.1	-	23, 24	3538
	AF165281.1	-	22, 23	3478
	AF285167.1	-	24, 25	3828
	AJ012376.1	-	22, 23	3478
	BC146856.1	-	24, 25	3752	9056784

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_178095, XM_008763710, AY208182.
This siRNA also targets the following transcripts in Mouse: NM_013454, X75926, AK051920.

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter, primary active transporter, transporter

Gene Ontology Categories:

Process(es)

peptide secretion
protein lipidation
phagocytosis, engulfment
lysosome organization
G-protein coupled receptor signaling pathway
response to nutrient
cholesterol metabolic process
negative regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
endosomal transport
positive regulation of cAMP biosynthetic process
intracellular cholesterol transport
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
high-density lipoprotein particle assembly
response to laminar fluid shear stress
apolipoprotein A-I-mediated signaling pathway
lipoprotein metabolic process
response to drug
cholesterol homeostasis
reverse cholesterol transport
phospholipid translocation
interleukin-1 beta secretion
phospholipid homeostasis
response to low-density lipoprotein particle
platelet dense granule organization
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to cholesterol
anion transmembrane transport

Function(s)

receptor binding
protein binding
ATP binding
phospholipid binding
phospholipid transporter activity
anion transmembrane transporter activity
cholesterol binding
cholesterol transporter activity
syntaxin binding
small GTPase binding
apolipoprotein binding
apolipoprotein A-I binding
apolipoprotein A-I receptor activity
ATPase activity, coupled to transmembrane movement of substances
ATPase binding