s8644 Validated

• Gene Symbol: MECP2
• Gene Name: methyl-CpG binding protein 2
• Gene Aliases: AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
• Chromosome Location: Chr.X: 154021800 - 154097731 on Build GRCh38
• UniGene ID: Hs.200716
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MECP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001110792.1	NP_001104262.1	3	763
	NM_001316337.1	NP_001303266.1	5	1055
	NM_004992.3	NP_004983.1	4	887
	XM_005274682.4	XP_005274739.1	5	961
	XM_006724819.3	XP_006724882.1	4	638
	XM_011531166.2	XP_011529468.1	3	774
	XM_017029533.1	XP_016885022.1	7	1387
GenBank mRNA	AF158180.1	-	4	828
	AJ132917.1	-	3	736
	AK289444.1	-	4	862
	AY541280.1	-	3	704
	BC011612.1	-	3	745	3956518
	BX538060.1	-	3	753
	GQ203293.1	-	4	887
	GQ203294.1	-	4	887
	GQ203295.1	-	4	887
	GQ896382.1	-	4	887
	GU479943.1	-	4	887
	GU812285.1	-	3	662
	GU812286.1	-	3	661
	HM020402.1	-	4	887
	HM156732.1	-	4	887
	HM156733.1	-	4	887
	HQ127345.1	-	3	661
	HQ141377.1	-	3	661
	HQ141378.1	-	4	887
	HQ154629.1	-	4	887
	KU178174.1	-	3	661
	L37298.1	-	3	742
	X89430.1	-	2	632
	X99686.1	-	3	735
	Y12643.1	-	3	725

More Information

Matching Taqman Gene Expression Assay:

Hs00172845_m1

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
behavioral fear response
response to hypoxia
startle response
neurological system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by neurological system process
inositol metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
glutamine metabolic process
cellular biogenic amine metabolic process
synapse assembly
heart development
respiratory gaseous exchange
long-term memory
locomotory behavior
protein localization
glucocorticoid metabolic process
positive regulation of cell proliferation
adult locomotory behavior
visual learning
response to radiation
pathogenesis
post-embryonic development
response to ionizing radiation
response to lead ion
dendrite development
histone methylation
histone acetylation
proprioception
sensory perception of pain
cerebellum development
ventricular system development
negative regulation of histone methylation
cardiolipin metabolic process
response to estradiol
negative regulation of histone acetylation
social behavior
neuron maturation
negative regulation of neuron apoptotic process
regulation of DNA methylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylcholine metabolic process
negative regulation of astrocyte differentiation
catecholamine secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
long-term synaptic potentiation

Function(s)

four-way junction DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
mRNA binding
protein binding
transcription factor binding
methyl-CpG binding
double-stranded methylated DNA binding
protein domain specific binding
chromatin DNA binding
siRNA binding
histone deacetylase binding
poly(A) RNA binding
unmethylated CpG binding
protein N-terminus binding