s9293

• Gene Symbol: NBN
• Gene Name: nibrin
• Gene Aliases: AT-V1, AT-V2, ATV, NBS, NBS1, P95
• Chromosome Location: Chr.8: 89933336 - 89984733 on Build GRCh38
• UniGene ID: Hs.492208
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NBN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001024688.2	NP_001019859.1	13	2102
	NM_002485.4	NP_002476.2	12	1999
	XM_011517045.1	XP_011515347.1	13	1932
	XM_017013460.1	XP_016868949.1	14	2083
	XM_017013461.1	XP_016868950.1	11	1822
	XM_017013462.1	XP_016868951.1	12	2007
GenBank mRNA	AF051334.1	-	12	1940
	AF058696.2	-	12	1941
	AK001017.1	-	13	1878
	AK223256.1	-	12	1943
	AK289848.1	-	12	1995
	AK312410.1	-	12	2001
	BC136802.1	-	12	1958	9020792
	BC136803.1	-	12	1958	9020793
	BC144413.1	-	12	1958
	BC146797.1	-	12	1951	8860301
	BX640816.1	-	13	2050

More Information

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
telomere maintenance
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
blastocyst growth
DNA replication
double-strand break repair
double-strand break repair via nonhomologous end joining
cell cycle arrest
mitotic cell cycle checkpoint
mitotic G2 DNA damage checkpoint
cell proliferation
regulation of DNA-dependent DNA replication initiation
DNA damage response, signal transduction by p53 class mediator
telomeric 3' overhang formation
positive regulation of protein autophosphorylation
positive regulation of telomere maintenance
DNA duplex unwinding
positive regulation of kinase activity
isotype switching
neuromuscular process controlling balance
meiotic cell cycle
intrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
negative regulation of telomere capping

Function(s)

damaged DNA binding
ATP-dependent DNA helicase activity
protein binding
transcription factor binding
protein N-terminus binding