s9417 Validated

• Gene Symbol: NEDD4
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-1, RPF1
• Chromosome Location: Chr.15: 55826917 - 55993746 on Build GRCh38
• UniGene ID: Hs.1565
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEDD4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001284338.1	NP_001271267.1	20	3781
	NM_001284339.1	NP_001271268.1	20	3733
	NM_001284340.1	NP_001271269.1	19	3730
	NM_006154.3	NP_006145.2	24	2415
	NM_198400.3	NP_940682.2	17	3565
	XM_011521624.2	XP_011519926.1	23	2180
	XM_011521625.2	XP_011519927.1	25	2353
	XM_011521626.1	XP_011519928.1	23	2197
	XM_011521627.1	XP_011519929.1	21	2020
GenBank mRNA	AK304394.1	-	24	2281
	AK307541.1	-	20	2032
	AL832063.1	-	17	3566
	AL832359.1	-	19	2253
	AL833300.1	-	20	2763
	AY550969.1	-	24	2294
	BC035707.1	-	24	2259
	BC136605.1	-	20	3758	9020595
	BC144284.1	-	20	3758	9052804
	BC144285.1	-	20	3710	9052805
	BC152452.1	-	24	2306	8862584
	BC152562.1	-	24	2306	8860509
	D42055.1	-	24	2306

More Information

Matching Taqman Gene Expression Assay:

Hs00299364_m1

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

adaptive immune response
outflow tract morphogenesis
endocardial cushion development
protein monoubiquitination
protein targeting to lysosome
lysosomal transport
neuromuscular junction development
negative regulation of sodium ion transport
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
positive regulation of phosphatidylinositol 3-kinase signaling
response to denervation involved in regulation of muscle adaptation
regulation of macroautophagy
protein ubiquitination
transmission of virus
negative regulation of vascular endothelial growth factor receptor signaling pathway
neuron projection development
receptor internalization
receptor catabolic process
cellular response to UV
regulation of ion transmembrane transport
T cell activation
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
glucocorticoid receptor signaling pathway
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
development involved in symbiotic interaction
positive regulation of protein catabolic process
positive regulation of nucleocytoplasmic transport
blood vessel morphogenesis
regulation of dendrite morphogenesis
regulation of synapse organization
progesterone receptor signaling pathway
response to calcium ion
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity
negative regulation of sodium ion transmembrane transporter activity

Function(s)

protein binding
protein C-terminus binding
ligase activity
sodium channel inhibitor activity
protein domain specific binding
beta-2 adrenergic receptor binding
ubiquitin binding
phosphoserine binding
phosphothreonine binding
ubiquitin protein ligase activity
RNA polymerase binding
proline-rich region binding