s961

• Gene Symbol: ACTN4
• Gene Name: actinin alpha 4
• Gene Aliases: ACTININ-4, FSGS, FSGS1
• Chromosome Location: Chr.19: 38647616 - 38730532 on Build GRCh38
• UniGene ID: Hs.270291
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ACTN4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004924.5	NP_004915.2	8	937
	XM_005259281.4	XP_005259338.1	8	937
	XM_017027331.1	XP_016882820.1	8	937
GenBank mRNA	AK299955.1	-	8	866
	AK304554.1	-	8	866
	AK309361.1	-	8	866
	AK309363.1	-	8	904
	AK309364.1	-	8	866
	BC005033.1	-	8	820	3842046
	D89980.1	-	8	814
	KU177881.1	-	8	807
	U48734.1	-	8	881

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031675, XM_008759185, XM_006228690, XM_006228688, U19893, and others.
This siRNA also targets the following transcripts in Mouse: NM_021895, BC087554, DQ303411, BC027032, DQ303410, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
platelet degranulation
protein transport
vesicle transport along actin filament
positive regulation of cell migration
positive regulation of sodium:proton antiporter activity
peroxisome proliferator activated receptor signaling pathway
regulation of apoptotic process
retinoic acid receptor signaling pathway
positive regulation of pinocytosis
actin filament bundle assembly
negative regulation of cellular component movement
positive regulation of cellular component movement
bicellular tight junction assembly
negative regulation of substrate adhesion-dependent cell spreading
positive regulation of NIK/NF-kappaB signaling
protein localization to bicellular tight junction
regulation of nucleic acid-templated transcription

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
nucleoside binding
actin binding
integrin binding
calcium ion binding
protein binding
ligand-dependent nuclear receptor transcription coactivator activity
chromatin DNA binding
nuclear hormone receptor binding
protein homodimerization activity
retinoic acid receptor binding
ion channel binding
poly(A) RNA binding
protein N-terminus binding
actin filament binding