s9622

• Gene Symbol: NOS3
• Gene Name: nitric oxide synthase 3
• Gene Aliases: ECNOS, eNOS
• Chromosome Location: Chr.7: 150991056 - 151014599 on Build GRCh38
• UniGene ID: Hs.647092
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOS3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000603.4	NP_000594.2	27	3805
	XM_017012232.1	XP_016867721.1	26	3562
	XM_017012233.1	XP_016867722.1	26	3461
GenBank mRNA	AF400594.1	-	26	3509
	AK223636.1	-	26	3529
	AK225827.1	-	26	3529
	AK292928.1	-	26	3562
	AK300390.1	-	24	3236
	AK302686.1	-	26	3463
	AK315213.1	-	26	3531
	BC063294.1	-	27	3801	30340813
	BC069465.1	-	26	3527	7262393
	M93718.1	-	26	3555
	M95296.1	-	26	3529

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008713, AK077896, AK143221, BC052636, U53142.

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

angiogenesis
ovulation from ovarian follicle
in utero embryonic development
blood vessel remodeling
regulation of sodium ion transport
regulation of the force of heart contraction by chemical signal
regulation of systemic arterial blood pressure by endothelin
arginine catabolic process
nitric oxide biosynthetic process
mitochondrion organization
nitric oxide mediated signal transduction
regulation of blood pressure
negative regulation of cell proliferation
response to heat
negative regulation of platelet activation
negative regulation of muscle hyperplasia
smooth muscle hyperplasia
removal of superoxide radicals
lung development
positive regulation of guanylate cyclase activity
lipopolysaccharide-mediated signaling pathway
response to fluid shear stress
negative regulation of potassium ion transport
endothelial cell migration
cell redox homeostasis
positive regulation of angiogenesis
negative regulation of blood pressure
positive regulation of vasodilation
regulation of blood vessel size
regulation of nitric-oxide synthase activity
negative regulation of hydrolase activity
negative regulation of calcium ion transport
oxidation-reduction process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

actin monomer binding
nitric-oxide synthase activity
iron ion binding
protein binding
calmodulin binding
FMN binding
heme binding
tetrahydrobiopterin binding
arginine binding
cadmium ion binding
flavin adenine dinucleotide binding
NADP binding
scaffold protein binding