s97503

• Gene Symbol: Kdm1a
• Gene Name: lysine (K)-specific demethylase 1A
• Gene Aliases: 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601
• Chromosome Location: Chr.4: 136550533 - 136602789 on Build GRCm38
• UniGene ID: Mm.28540
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Kdm1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133872.2	NP_598633.2	12	1650
GenBank mRNA	AK129170.1	-	12	1590
	BC059885.1	-	12	1637	6815975

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001009999, NM_015013, BC048134, AK290328, BC025362, and others.
This siRNA also targets the following transcripts in Rat: NM_001130098, EF688598.

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein demethylation
multicellular organism development
cell proliferation
regulation of primitive erythrocyte differentiation
positive regulation of neuron projection development
chromatin modification
pituitary gland development
granulocyte differentiation
negative regulation of protein binding
histone H3-K9 demethylation
histone H3-K4 demethylation
positive regulation of chromatin binding
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of erythrocyte differentiation
positive regulation of megakaryocyte differentiation
positive regulation of cell size
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
guanine metabolic process
positive regulation of hormone biosynthetic process
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
muscle cell development
oxidation-reduction process
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of transcription from RNA polymerase II promoter by histone modification
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation

Function(s)

RNA polymerase II transcription factor binding
p53 binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
N-ethylmaleimide reductase activity
oxidoreductase activity
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
demethylase activity
histone demethylase activity
histone demethylase activity (H3-K4 specific)
histone demethylase activity (H3-K9 specific)
histone demethylase activity (H3-dimethyl-K4 specific)
MRF binding
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
transcription regulatory region DNA binding
flavin adenine dinucleotide binding
androgen receptor binding
epoxyqueuosine reductase activity